EDIL3 encodes the EGF-like repeats and discoidin I-like domains 3 protein, also known as Del-1. This protein contains epidermal growth factor (EGF)-like repeats and discoidin I-like domains. It plays a role in regulating angiogenesis and inflammation. The protein promotes angiogenesis by interacting with integrin receptors, modulating the activity of endothelial cells. It is also involved in the NF-κB signaling pathway.
Abnormal expression of EDIL3 has been associated with various diseases, including cancer, where it may promote tumor angiogenesis and metastasis. In cardiovascular diseases, it can influence vascular remodeling. Currently, research is underway to develop drugs targeting EDIL3, aiming to provide new therapeutic options for related diseases.
Validated Data
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
EDIL3 Antibody (CSB-PA007399ESR1HU)
Validated Data
Western blot
All lanes: EDIL3 antibody at 3.09µg/ml
Lane 1: 293T whole cell lysate
Lane 2: Hela whole cell lysate
Lane 3: HepG2 whole cell lysate
Lane 4: K562 whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 54, 53 kDa
Observed band size: 54 kDa
Immunohistochemistry of paraffin-embedded human pancreatic cancer using CSB-PA007399ESR1HU at dilution of 1:100
Validated Data
Code: CSB-EL007399HU
Size: 96T,5×96T,10×96T
Sensitivity: 31.25 pg/mL
Detection Range: 125 pg/mL-8000 pg/mL
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
The following EDIL3 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
EDIL3 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA007399GA01HU | EDIL3 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
CSB-PA931107 | EDIL3 Antibody | Human,Mouse | ELISA,WB,IHC |
CSB-PA126136 | EDIL3 Antibody | Human,Mouse | ELISA,WB |
CSB-PA007399ESR1HU | EDIL3 Antibody | Human | ELISA, WB, IHC |
CSB-PA007399ESR2HU | EDIL3 Antibody | Human | ELISA, IHC |
EDIL3 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP007399HU CSB-EP007399HU CSB-MP007399HU CSB-EP007399HU-B |
Recombinant Human EGF-like repeat and discoidin I-like domain-containing protein 3 (EDIL3) | Yeast E.coli Mammalian cell In Vivo Biotinylation in E.coli |
CSB-BP007399HU | Recombinant Human EGF-like repeat and discoidin I-like domain-containing protein 3 (EDIL3) | Baculovirus |
EDIL3 ELISA Kit for Homo sapiens (Human)
Code | Product Name | Sample Types | Sensitivity |
---|---|---|---|
CSB-EL007399HU | Human EGF-like repeat and discoidin I-like domain-containing protein 3(EDIL3) ELISA kit | serum, plasma, tissue homogenates | 31.25 pg/mL |