EFNA1

EFNA1 encodes the protein Ephrin-A1. It is also commonly known as LERK-1. Ephrin-A1 functions as a ligand for Eph receptors, initiating bidirectional signaling upon binding. This interaction regulates cell adhesion, migration, and axon guidance. It's involved in the Eph/ephrin signaling pathway which is crucial for tissue patterning during development.
Aberrant Ephrin-A1 signaling has been linked to various diseases such as cancer, where it promotes tumor angiogenesis and metastasis. In drug development, targeting Ephrin-A1 is being explored. Some small - molecule inhibitors are under pre - clinical research, aiming to block the Eph/ephrin interaction and halt disease progression.

Validated Data

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

Activity
Measured by its binding ability in a functional ELISA. Immobilized Human EPHA2 (CSB-MP007722HUd7) at 2 μg/ml can bind Human EFNA1. The EC₅₀ is 5.859-7.758 ng/mL.

EFNA1 Antibody (CSB-PA007460ESR1HU)

Validated Data

Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA007460ESR1HU at dilution of 1:100

Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA007460ESR1HU at dilution of 1:100

Human Ephrin-A1(EFNA1) ELISA kit (CSB-EL007460HU)

Validated Data

Code: CSB-EL007460HU

Size: 96T,5×96T,10×96T

Sensitivity: 0.039 ng/mL

Detection Range: 0.156 ng/mL-10 ng/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

The following EFNA1 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

EFNA1 Antibodies

EFNA1 Proteins

EFNA1 ELISA Kits

EFNA1 Antibodies

EFNA1 Antibodies for Rattus norvegicus (Rat)

Code	Product Name	Species Reactivity	Application
CSB-PA007460LA01RA	Efna1 Antibody	Rat	ELISA

EFNA1 Antibodies for Homo sapiens (Human)

Code	Product Name	Species Reactivity	Application
CSB-PA007460ESR1HU	EFNA1 Antibody	Human	ELISA, IHC
CSB-PA551061	EFNA1 Antibody	Human,Mouse,Rat	ELISA,WB,IF
CSB-PA002367	EFNA1 Antibody	Human,Mouse,Rat	WB, IHC, IF, ELISA
CSB-PA256498	EFNA1 Antibody	Human,Mouse,Rat	ELISA,IHC
CSB-PA999540	EFNA1 Antibody	Human,Mouse,Rat	ELISA,IHC

EFNA1 Proteins

EFNA1 Proteins for Rattus norvegicus (Rat)

Code	Product Name	Source
CSB-EP007460RA	Recombinant Rat Ephrin-A1 (Efna1)	E.coli
CSB-EP007460RAe0	Recombinant Rat Ephrin-A1 (Efna1)	E.coli
CSB-YP007460RA	Recombinant Rat Ephrin-A1 (Efna1)	Yeast
CSB-BP007460RA CSB-MP007460RA CSB-EP007460RA-B	Recombinant Rat Ephrin-A1 (Efna1)	Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

EFNA1 Proteins for Homo sapiens (Human)

Code	Product Name	Source
CSB-YP007460HU CSB-BP007460HU CSB-MP007460HU CSB-EP007460HU-B	Recombinant Human Ephrin-A1 (EFNA1)	Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-EP007460HU	Recombinant Human Ephrin-A1 (EFNA1)	E.coli
CSB-AP005711HU	Recombinant Human Ephrin-A1 (EFNA1) (Active)	Mammalian cell
CSB-MP007460HU	Recombinant Human Ephrin-A1 (EFNA1) (Active)	Mammalian cell

EFNA1 Proteins for Mus musculus (Mouse)

Code	Product Name	Source
CSB-YP007460MO CSB-EP007460MO CSB-BP007460MO CSB-MP007460MO CSB-EP007460MO-B	Recombinant Mouse Ephrin-A1 (Efna1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-AP005771MO	Recombinant Mouse Ephrin-A1 (Efna1), partial (Active)	Mammalian cell

EFNA1 Proteins for Xenopus laevis (African clawed frog)

Code	Product Name	Source
CSB-YP007460XBE CSB-EP007460XBE CSB-BP007460XBE CSB-MP007460XBE CSB-EP007460XBE-B	Recombinant Xenopus laevis Ephrin-A1 (efna1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

EFNA1 Proteins for Bos taurus (Bovine)

Code	Product Name	Source
CSB-YP007460BO CSB-EP007460BO CSB-BP007460BO CSB-MP007460BO CSB-EP007460BO-B	Recombinant Bovine Ephrin-A1 (EFNA1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

EFNA1 ELISA Kit

EFNA1 ELISA Kit for Homo sapiens (Human)

Code	Product Name	Sample Types	Sensitivity
CSB-EL007460HU	Human Ephrin-A1(EFNA1) ELISA kit	serum, plasma, tissue homogenates, cell lysates	0.039 ng/mL

EFNA1 ELISA Kit for Mus musculus (Mouse)

Code	Product Name	Sample Types	Sensitivity
CSB-EL007460MO	Mouse Ephrin-A1(EFNA1) ELISA kit	serum, plasma, tissue homogenates	23.43 pg/mL

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EFNA1

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