EPAS1, also known as HIF-2α, is a transcription factor encoded by genes in humans and mammals. It plays a crucial role under hypoxic conditions, helping cells adapt by regulating a suite of genes tied to angiogenesis, erythropoiesis, and energy metabolism. Biologically, EPAS1 is key to preserving physiological balance in the face of oxygen scarcity. Moreover, it's intricately linked to the pathogenesis and progression of diseases such as cancer and cardiovascular diseases.
EPAS1 Recombinant Monoclonal Antibody (CSB-RA904931A0HU)
Validated Data
Immunofluorescence staining of Hela Cells with CSB-RA904931A0HU at 1:50, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeated by 0.2% TritonX-100, and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4℃. Nuclear DNA was labeled in blue with DAPI. The secondary antibody was FITC-conjugated AffiniPure Goat Anti-Rabbit IgG (H+L).
The following EPAS1 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
EPAS1 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA244646 | EPAS1 Antibody | Human | ELISA,WB |
CSB-PA005478 | EPAS1 Antibody | Human,Mouse,Rat | WB, ELISA |
CSB-PA213807 | Acetyl-EPAS1 (K385) Antibody | Human,Mouse,Rat | WB,ELISA |
CSB-PA860780LA01HU | EPAS1 Antibody | Human | ELISA, IHC, IF |
CSB-PA860780LB01HU | EPAS1 Antibody, HRP conjugated | Human | ELISA |
CSB-PA860780LC01HU | EPAS1 Antibody, FITC conjugated | Human | |
CSB-PA860780LD01HU | EPAS1 Antibody, Biotin conjugated | Human | ELISA |
CSB-RA904931A0HU | EPAS1 Recombinant Monoclonal Antibody | Human | ELISA, IF |
EPAS1 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP860780HU CSB-EP860780HU CSB-BP860780HU CSB-MP860780HU CSB-EP860780HU-B |
Recombinant Human Endothelial PAS domain-containing protein 1 (EPAS1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
EPAS1 ELISA Kit for Homo sapiens (Human)
Code | Product Name | Sample Types | Sensitivity |
---|---|---|---|
CSB-E12113h | Human hypoxia-inducible factor 2(HIF-2) ELISA kit | serum, plasma, tissue homogenates, cell lysates | 15.6 pg/mL |