ERO1-like protein beta is a protein in humans that is encoded by ERO1B gene. Oxidoreductase involved in disulfide bond formation in the endoplasmic reticulum. Efficiently reoxidizes P4HB/PDI, the enzyme catalyzing protein disulfide formation, in order to allow P4HB to sustain additional rounds of disulfide formation. Other protein disulfide isomerase family members can also be reoxidized, but at lower rates compared to P4HB, including PDIA2 (50% of P4HB reoxidation rate), as well as PDIA3, PDIA4, PDIA6 and NXNDC12 (<10%). Following P4HB reoxidation, passes its electrons to molecular oxygen via FAD, leading to the production of reactive oxygen species (ROS) in the cell. May be involved in oxidative proinsulin folding in pancreatic cells, hence may play a role in glucose homeostasis.
The following ERO1B reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
ERO1B Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA007798GA01HU | ERO1LB Antibody |
Human,Mouse | ELISA,WB,IHC |
CSB-PA774834LA01HU | ERO1B Antibody |
Human, Mouse | ELISA, WB, IHC |
CSB-PA774834LB01HU | ERO1B Antibody, HRP conjugated |
Human | ELISA |
CSB-PA774834LC01HU | ERO1B Antibody, FITC conjugated |
Human | |
CSB-PA774834LD01HU | ERO1B Antibody, Biotin conjugated |
Human | ELISA |
ERO1B Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP774834HU CSB-EP774834HU CSB-BP774834HU CSB-MP774834HU CSB-EP774834HU-B |
Recombinant Human ERO1-like protein beta (ERO1LB) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ERO1B Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
---|---|---|
CSB-YP837127MO CSB-EP837127MO CSB-BP837127MO CSB-MP837127MO CSB-EP837127MO-B |
Recombinant Mouse ERO1-like protein beta (Ero1lb) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |