F8

F8, or coagulation factor VIII, is a plasma glycoprotein synthesised in the liver and encoded by the F8 gene.F8 plays a key role in the coagulation process, acting as a cofactor for coagulation factor IXa, and participating in the activation of coagulation factor X, thereby promoting blood coagulation.The source of F8 is mainly hepatocytes.Mature F8 consists of 2332 amino acids, and has a molecular weight of about 300 kDa.F8's The biological significance of F8 is to maintain the balance of blood coagulation and haemostasis. Deficiency or abnormal function of F8 can lead to haemorrhagic diseases such as haemophilia A.

Validated Data

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

F8 Antibody (CSB-PA007932LA01HU)

Validated Data

Immunohistochemistry of paraffin-embedded human placenta tissue using CSB-PA007932LA01HU at dilution of 1:100

Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA007932LA01HU at dilution of 1:100

Immunofluorescent analysis of Hela cells using CSB-PA007932LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

The following F8 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

F8 Antibodies

F8 Proteins

F8 ELISA Kits

F8 Antibodies

F8 Antibodies for Homo sapiens (Human)

Code	Product Name	Species Reactivity	Application
CSB-PA007932GA01HU	F8 Antibody	Human	ELISA,IF
CSB-PA002462	F8 Antibody	Human,Mouse	WB, IHC, ELISA
CSB-PA007932LA01HU	F8 Antibody	Human	ELISA, IHC, IF
CSB-PA007932LB01HU	F8 Antibody, HRP conjugated	Human	ELISA
CSB-PA007932LC01HU	F8 Antibody, FITC conjugated	Human
CSB-PA007932LD01HU	F8 Antibody, Biotin conjugated	Human	ELISA

F8 Proteins

F8 Proteins for Sus scrofa (Pig)

Code	Product Name	Source
CSB-YP007932PI CSB-BP007932PI CSB-MP007932PI CSB-EP007932PI-B	Recombinant Pig Coagulation factor VIII (F8), partial	Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

F8 Proteins for Homo sapiens (Human)

Code	Product Name	Source
CSB-YP007932HU CSB-BP007932HU CSB-MP007932HU CSB-EP007932HU-B	Recombinant Human Coagulation factor VIII (F8)	Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-EP007932HU	Recombinant Human Coagulation factor VIII (F8)	E.coli

F8 Proteins for Canis lupus familiaris (Dog) (Canis familiaris)

Code	Product Name	Source
CSB-YP007932DO CSB-EP007932DO CSB-BP007932DO CSB-MP007932DO CSB-EP007932DO-B	Recombinant Dog Coagulation factor VIII (F8), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli