FGFR4, or fibroblast growth factor receptor 4, is an important tyrosine kinase receptor encoded by the FGFR4 gene and distributed widely in tissues such as bones, kidneys, and liver. It combines with fibroblast growth factor to activate downstream signaling pathways like RAS/RAF/MEK/ERK and PI3K/AKT, regulating cell proliferation, differentiation, migration, and survival. FGFR4 is crucial for bone development and kidney function maintenance, and its abnormal activity is linked to diseases such as bone malformations, cancer, and kidney diseases.
FGFR4 Recombinant Monoclonal Antibody (CSB-RA927449A0HU)
Validated Data
IHC image of CSB-RA927449A0HU diluted at 1:100 and staining in paraffin-embedded human breast cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4℃ overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.
The following FGFR4 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
FGFR4 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA008648GA01HU | FGFR4 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
CSB-PA556085 | FGFR4 Antibody | Human,Mouse,Rat | ELISA,WB |
CSB-PA977910 | Phospho-FGFR4 (Tyr642) Antibody | Human,Mouse,Rat | ELISA,WB |
CSB-PA008250 | Phospho-FGFR4 (Y642) Antibody | Human,Mouse,Rat | WB, ELISA |
CSB-PA604644 | FGFR4 Antibody | Human | WB, ELISA |
CSB-PA008648LA01HU | FGFR4 Antibody | Human | ELISA, IHC, IF |
CSB-PA008648LB01HU | FGFR4 Antibody, HRP conjugated | Human | ELISA |
CSB-PA008648LC01HU | FGFR4 Antibody, FITC conjugated | Human | |
CSB-PA008648LD01HU | FGFR4 Antibody, Biotin conjugated | Human | ELISA |
CSB-RA927449A0HU | FGFR4 Recombinant Monoclonal Antibody | Human | ELISA, IHC |
FGFR4 Antibodies for Danio rerio (Zebrafish) (Brachydanio rerio)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA008648XA01DIL | fgfr4 Antibody | Danio rerio (Zebrafish) (Brachydanio rerio) | ELISA, WB (ensure identification of antigen) |
FGFR4 Proteins for Danio rerio (Zebrafish) (Brachydanio rerio)
Code | Product Name | Source |
---|---|---|
CSB-YP008648DIL CSB-EP008648DIL CSB-BP008648DIL CSB-MP008648DIL CSB-EP008648DIL-B |
Recombinant Danio rerio Fibroblast growth factor receptor 4 (fgfr4), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
FGFR4 Proteins for Coturnix coturnix (Common quail) (Tetrao coturnix)
Code | Product Name | Source |
---|---|---|
CSB-YP008648CRA CSB-EP008648CRA CSB-BP008648CRA CSB-MP008648CRA CSB-EP008648CRA-B |
Recombinant Coturnix coturnix Fibroblast growth factor receptor 4 (FGFR4), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
FGFR4 Proteins for Pleurodeles waltl (Iberian ribbed newt)
Code | Product Name | Source |
---|---|---|
CSB-YP008648EWZ CSB-EP008648EWZ CSB-BP008648EWZ CSB-MP008648EWZ CSB-EP008648EWZ-B |
Recombinant Pleurodeles waltl Fibroblast growth factor receptor 4 (FGFR4), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
FGFR4 Proteins for Xenopus laevis (African clawed frog)
Code | Product Name | Source |
---|---|---|
CSB-YP008648XBE CSB-EP008648XBE CSB-BP008648XBE CSB-MP008648XBE CSB-EP008648XBE-B |
Recombinant Xenopus laevis Fibroblast growth factor receptor 4 (fgfr4), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
FGFR4 Proteins for Rattus norvegicus (Rat)
Code | Product Name | Source |
---|---|---|
CSB-YP008648RA CSB-EP008648RA CSB-BP008648RA CSB-MP008648RA CSB-EP008648RA-B |
Recombinant Rat Fibroblast growth factor receptor 4 (Fgfr4), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
FGFR4 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-CF008648HU | Recombinant Human Fibroblast growth factor receptor 4 (FGFR4) | in vitro E.coli expression system |
CSB-YP008648HU1 CSB-EP008648HU1 CSB-BP008648HU1 CSB-MP008648HU1 CSB-EP008648HU1-B |
Recombinant Human Fibroblast growth factor receptor 4 (FGFR4), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |