Frizzled-7 is a protein in humans that is encoded by FZD7 gene. Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues.
The following FZD7 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
FZD7 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA009110GA01HU | FZD7 Antibody | Human,Mouse,Rat | ELISA,WB |
CSB-PA002581 | FZD7 Antibody | Human,Mouse | WB, IF, ELISA |
CSB-PA009110LA01HU | FZD7 Antibody | Human | ELISA, WB, IHC |
CSB-PA009110LB01HU | FZD7 Antibody, HRP conjugated | Human | ELISA |
CSB-PA009110LC01HU | FZD7 Antibody, FITC conjugated | Human |
FZD7 Proteins for Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
Code | Product Name | Source |
---|---|---|
CSB-CF704724XBF | Recombinant Xenopus tropicalis Frizzled-7 (fzd7) | in vitro E.coli expression system |
CSB-YP704724XBF1 CSB-EP704724XBF1 CSB-BP704724XBF1 CSB-MP704724XBF1 CSB-EP704724XBF1-B |
Recombinant Xenopus tropicalis Frizzled-7 (fzd7), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
FZD7 Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
---|---|---|
CSB-CF730721MO | Recombinant Mouse Frizzled-7 (Fzd7) | in vitro E.coli expression system |
CSB-YP730721MO1 CSB-EP730721MO1 CSB-BP730721MO1 CSB-MP730721MO1 CSB-EP730721MO1-B |
Recombinant Mouse Frizzled-7 (Fzd7), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
FZD7 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-CF009110HU | Recombinant Human Frizzled-7 (FZD7) | in vitro E.coli expression system |
CSB-YP009110HU1 CSB-EP009110HU1 CSB-BP009110HU1 CSB-MP009110HU1 CSB-EP009110HU1-B |
Recombinant Human Frizzled-7 (FZD7), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
FZD7 Proteins for Gallus gallus (Chicken)
Code | Product Name | Source |
---|---|---|
CSB-CF009110CH | Recombinant Chicken Frizzled-7 (FZD7) | in vitro E.coli expression system |
CSB-EP009110CH1 | Recombinant Chicken Frizzled-7 (FZD7), partial,Escherichia Coli | E.coli |
CSB-BP009110CH1 | Recombinant Chicken Frizzled-7 (FZD7), partial,Baculovirus | Baculovirus |
CSB-MP009110CH1 | Recombinant Chicken Frizzled-7 (FZD7), partial,Mammalian cell | Mammalian cell |
CSB-YP009110CH1 | Recombinant Chicken Frizzled-7 (FZD7), partial,Yeast | Yeast |