GAS6, full name growth arrest-specific 6. It is a secreted glycoprotein regulating cell survival, proliferation, coagulation and signal transduction, maintaining vascular homeostasis and immune balance. Abnormal GAS6 overexpression promotes tumor proliferation and metastasis, and correlates with thrombosis and cardiovascular diseases. GAS6 inhibitors are under preclinical research for anti-tumor and cardiovascular therapy.
Recombinant Human Growth arrest-specific protein 6 (GAS6) (Active) (CSB-MP619872HUd7)
Validated Data
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Activity
Measured by its binding ability in a functional ELISA. Immobilized Human GAS6 at 4 μg/ml can bind Human AXL (CSB-MP326981HUd9). The EC50 is 1.100-1.324 ng/mL.
Activity
Human AXL (CSB-MP326981HUd9) captured on Protein A Chip can bind Recombinant Human GAS6 with an affinity constant of 3.65 nM as detected by MetaSPR Assay (WeSPRTM 200).
Activity
Measured by its binding ability in a functional ELISA. Immobilized Human GAS6 at 2 μg/ml can bind Anti-GAS6 recombinant antibody (CSB-RA619872MA1HU). The EC50 is 12.31-14.86 ng/mL.
Activity
GAS6 Recombinant Monoclonal Antibody (CSB-RA619872MA1HU) captured on Protein A Chip can bind Recombinant Human GAS6 with an affinity constant of 0.767 nM as detected by MetaSPR Assay (WeSPRTM 200).
Recombinant Macaca fascicularis Growth arrest specific 6 (GAS6) (CSB-MP5039MOV)
Validated Data
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
The purity of GAS6 was greater than 95% as determined by SEC-HPLC
GAS6 Recombinant Monoclonal Antibody (CSB-RA619872MA1HU)
Validated Data
The Binding Activity of Human GAS6 with Anti-GAS6 Recombinant Antibody
Activity: Measured by its binding ability in a functional ELISA. Immobilized Human GAS6 (CSB-MP619872HUd7) at 2 μg/mL can bind Anti-GAS6 recombinant antibody. The EC50 is 12.31-14.86 ng/mL.
The Binding Activity of Human GAS6 with Anti-GAS6 Recombinant Antibody
Activity:GAS6 Recombinant Monoclonal Antibody captured on Protein A Chip can bind Recombinant Human GAS6 (CSB-MP619872HUd7) with an affinity constant of 0.767 nM as detected by MetaSPR Assay (WeSPRTM 200).
Human Growth arrest-specific protein 6(GAS6) ELISA kit (CSB-EL009270HU)
Validated Data
Code: CSB-EL009270HU
Size: 96T,5×96T,10×96T
Sensitivity: 0.195 ng/mL
Detection Range: 0.78 ng/mL-50 ng/mL
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
The following GAS6 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
GAS6 Antibodies for Homo sapiens (Human)
| Code | Product Name | Species Reactivity | Application |
|---|---|---|---|
| CSB-PA002641 | GAS6 Antibody | Human | WB, IHC, ELISA |
| CSB-PA778945 | GAS6 Antibody | Human | ELISA,IHC |
| CSB-PA108949 | GAS6 Antibody | Human | ELISA,IHC |
| CSB-PA619872LA01HU | GAS6 Antibody | Human | ELISA, WB |
| CSB-PA619872LC01HU | GAS6 Antibody, FITC conjugated | Human | |
| CSB-PA619872LD01HU | GAS6 Antibody, Biotin conjugated | Human | ELISA |
| CSB-RA619872MA1HU | GAS6 Recombinant Monoclonal Antibody | Human | ELISA, SPR |
GAS6 Proteins for Homo sapiens (Human)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP619872HU | Recombinant Human Growth arrest-specific protein 6 (GAS6),Yeast | Yeast |
| CSB-EP619872HU | Recombinant Human Growth arrest-specific protein 6 (GAS6),Escherichia Coli | E.coli |
| CSB-BP619872HU | Recombinant Human Growth arrest-specific protein 6 (GAS6),Baculovirus | Baculovirus |
| CSB-MP619872HU | Recombinant Human Growth arrest-specific protein 6 (GAS6),Mammalian cell | Mammalian cell |
| CSB-MP619872HUd7 | Recombinant Human Growth arrest-specific protein 6 (GAS6) (Active) | Mammalian cell |
GAS6 ELISA Kit for Homo sapiens (Human)
| Code | Product Name | Sample Types | Sensitivity |
|---|---|---|---|
| CSB-EL009270HU | Human Growth arrest-specific protein 6(GAS6) ELISA kit | serum, plasma, tissue homogenates | 0.195 ng/mL |