GDF11

GDF11, or Growth Differentiation Factor 11, also known as VHO, BMP11, or BMP-11, is a secreted protein encoded by a human gene and is a member of the Transforming Growth Factor-beta (TGF-β) superfamily. GDF11 can bind to TGF-β receptors, leading to the recruitment and activation of SMAD family transcription factors, thereby regulating gene expression. GDF11 plays a role in the development of the nervous system and other organ systems and may regulate the aging process.
Current research on GDF11 primarily focuses on the aging process and age-related diseases, including the promotion of cardiomyocyte proliferation, neuronal regeneration, and the proliferation and function of hematopoietic stem cells. The broad biological effects of GDF11 may include reversing cellular senescence during the aging process, reversing age-related pathological changes, and regulating organ regeneration following injury.

Validated Data

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-EP009344HU could indicate that this peptide derived from E.coli-expressed Homo sapiens (Human) GDF11.

GDF11 Antibody (CSB-PA105485)

Validated Data

The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using CSB-PA105485(GDF11 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: ×200)

The image on the left is immunohistochemistry of paraffin-embedded Human lymphoma tissue using CSB-PA105485(GDF11 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: ×200)

Human Growth/differentiation factor 11(GDF11) ELISA kit (CSB-EL009344HU)

Validated Data

Code: CSB-EL009344HU

Size: 96T,5×96T,10×96T

Sensitivity: 7 pg/mL

Detection Range: 28 pg/mL-1800 pg/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

The following GDF11 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

GDF11 Antibodies

GDF11 Proteins

GDF11 ELISA Kits

GDF11 Antibodies

GDF11 Antibodies for Homo sapiens (Human)

Code	Product Name	Species Reactivity	Application
CSB-PA105485	GDF11 Antibody	Human,Mouse,Rat	ELISA,IHC
CSB-PA009344ZA01HU	GDF11 Antibody	Homo sapiens	ELISA, WB (ensure identification of antigen)
CSB-PA009344LA01HU	GDF11 Antibody	Human	ELISA, IHC
CSB-PA009344LB01HU	GDF11 Antibody, HRP conjugated	Human	ELISA
CSB-PA009344LC01HU	GDF11 Antibody, FITC conjugated	Human
CSB-PA009344LD01HU	GDF11 Antibody, Biotin conjugated	Human	ELISA

GDF11 Proteins

GDF11 Proteins for Homo sapiens (Human)

Code	Product Name	Source
CSB-YP009344HU CSB-BP009344HU CSB-MP009344HU CSB-EP009344HU-B	Recombinant Human Growth/differentiation factor 11 (GDF11)	Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-EP009344HU	Recombinant Human Growth/differentiation factor 11 (GDF11)	E.coli

GDF11 ELISA Kit

GDF11 ELISA Kit for Homo sapiens (Human)

Code	Product Name	Sample Types	Sensitivity
CSB-EL009344HU	Human Growth/differentiation factor 11(GDF11) ELISA kit	serum, plasma, tissue homogenates	7 pg/mL

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GDF11

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