Glutamate receptor 4 is a protein in humans that is encoded by GRIA4 gene. Receptor for glutamate that functions as ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate.
The following GRIA4 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
GRIA4 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA008958 | Phospho-GRIA4 (S862) Antibody |
Human,Mouse,Rat | WB, IHC, ELISA |
CSB-PA008959 | GRIA4 Antibody |
Human,Mouse,Rat | WB, IHC, ELISA |
CSB-PA080176 | GRIA4 Antibody |
Human,Rat | WB, IHC |
CSB-PA009901LA01HU | GRIA4 Antibody |
Human | ELISA, IHC, IF |
CSB-PA009901LB01HU | GRIA4 Antibody, HRP conjugated |
Human | ELISA |
CSB-PA009901LC01HU | GRIA4 Antibody, FITC conjugated |
Human | |
CSB-PA009901LD01HU | GRIA4 Antibody, Biotin conjugated |
Human | ELISA |
GRIA4 Proteins for Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)
Code | Product Name | Source |
---|---|---|
CSB-YP653640MOV CSB-EP653640MOV CSB-BP653640MOV CSB-MP653640MOV CSB-EP653640MOV-B |
Recombinant Macaca fascicularis Glutamate receptor 4 (GRIA4), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
GRIA4 Proteins for Rattus norvegicus (Rat)
Code | Product Name | Source |
---|---|---|
CSB-YP009901RA CSB-EP009901RA CSB-BP009901RA CSB-MP009901RA CSB-EP009901RA-B |
Recombinant Rat Glutamate receptor 4 (Gria4), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
GRIA4 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP009901HU CSB-EP009901HU CSB-BP009901HU CSB-MP009901HU CSB-EP009901HU-B |
Recombinant Human Glutamate receptor 4 (GRIA4), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |