Glutathione S-transferase Pi 1 (GSTP1), also known as GST-pi, is a phase II metabolic enzyme. It catalyzes the conjugation of glutathione to electrophilic compounds—including reactive oxygen species and xenobiotics—neutralizing their toxicity and maintaining cellular redox balance.
GSTP1 regulates the MAPK/ERK pathway by sequestering JNK, inhibiting its activation. Overexpressed in breast, prostate, and lung cancers, it contributes to chemotherapy resistance. Inhibitors like ethacrynic acid analogs are being explored to reverse this resistance, while GSTP1 expression levels serve as a prognostic biomarker for multiple malignancies.
Recombinant Human Glutathione S-transferase P (GSTP1) (CSB-YP009989HU)
Validated Data
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
GSTP1 Recombinant Monoclonal Antibody (CSB-RA178104A0HU)
Validated Data
Western Blot
Positive WB detected in: HepG2 whole cell lysate, Jurkat whole cell lysate, PC-3 whole cell lysate, K562 whole cell lysate, HL-60 whole cell lysate, Mouse Brain whole cell lysate, Rat Brain whole cell lysate
All lanes: GSTP1 antibody at 1:1000
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 24 kDa
Observed band size: 24 kDa
IHC image of CSB-RA178104A0HU diluted at 1:100 and staining in paraffin-embedded human kidney tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4℃ overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.
Human glutathione S-transferases,GSTpi ELISA Kit (CSB-E09032h)
Validated Data
Code: CSB-E09032h
Size: 96T,5×96T,10×96T
Sensitivity: 0.39 ng/mL
Detection Range: 1.56 ng/mL-100 ng/mL
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
The following GSTP1 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
GSTP1 Antibodies for Homo sapiens (Human)
| Code | Product Name | Species Reactivity | Application |
|---|---|---|---|
| CSB-PA009989GA01HU | GSTP1 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA10334A0Rb | GSTP1 Antibody | Human | ELISA, WB |
| CSB-PA10334D0Rb | GSTP1 Antibody, Biotin conjugated | Human | ELISA |
| CSB-PA10337A0Rb | GSTP1 Antibody | Human | ELISA |
| CSB-PA584245 | GSTP1 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA949648 | GSTP1 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-RA178104A0HU | GSTP1 Recombinant Monoclonal Antibody | Human, Mouse, Rat | ELISA, WB, IHC |
GSTP1 Antibodies for Rattus norvegicus (Rat)
| Code | Product Name | Species Reactivity | Application |
|---|---|---|---|
| CSB-PA009989HA01RA | Gstp1 Antibody | Rat, Human | ELISA, WB |
GSTP1 Antibodies for Mus musculus (Mouse)
| Code | Product Name | Species Reactivity | Application |
|---|---|---|---|
| CSB-PA009989HA01MO | Gstp1 Antibody | Mouse, Human | ELISA, WB |
| CSB-PA009989HD01MO | Gstp1 Antibody, Biotin conjugated | Mouse | ELISA |
GSTP1 Antibodies for Cricetulus longicaudatus (Long-tailed dwarf hamster) (Chinese hamster)
| Code | Product Name | Species Reactivity | Application |
|---|---|---|---|
| CSB-PA009989ZA01DXV | GSTP1 Antibody | Cricetulus longicaudatus | ELISA, WB (ensure identification of antigen) |
GSTP1 Proteins for Sus scrofa (Pig)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP009989PI CSB-EP009989PI CSB-BP009989PI CSB-MP009989PI CSB-EP009989PI-B |
Recombinant Pig Glutathione S-transferase P (GSTP1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
GSTP1 Proteins for Mus musculus (Mouse)
| Code | Product Name | Source |
|---|---|---|
| CSB-EP009989MO | Recombinant Mouse Glutathione S-transferase P 1 (Gstp1) | E.coli |
| CSB-YP009989MO | Recombinant Mouse Glutathione S-transferase P 1 (Gstp1) | Yeast |
| CSB-BP009989MO CSB-MP009989MO CSB-EP009989MO-B |
Recombinant Mouse Glutathione S-transferase P 1 (Gstp1) | Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
GSTP1 Proteins for Bos taurus (Bovine)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP009989BO CSB-EP009989BO CSB-BP009989BO CSB-MP009989BO CSB-EP009989BO-B |
Recombinant Bovine Glutathione S-transferase P (GSTP1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
GSTP1 Proteins for Rattus norvegicus (Rat)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP009989RA CSB-BP009989RA CSB-MP009989RA CSB-EP009989RA-B |
Recombinant Rat Glutathione S-transferase P (Gstp1) | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP009989RA | Recombinant Rat Glutathione S-transferase P (Gstp1) | E.coli |
GSTP1 Proteins for Homo sapiens (Human)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP009989HU | Recombinant Human Glutathione S-transferase P (GSTP1) | Yeast |
| CSB-EP009989HU | Recombinant Human Glutathione S-transferase P (GSTP1) | E.coli |
| CSB-BP009989HU CSB-MP009989HU CSB-EP009989HU-B |
Recombinant Human Glutathione S-transferase P (GSTP1) | Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP009989HUe0 | Recombinant Human Glutathione S-transferase P (GSTP1) | E.coli |
| CSB-YP009989HUb0 | Recombinant Human Glutathione S-transferase P (GSTP1) | Yeast |
| CSB-EP009989HUa0 | Recombinant Human Glutathione S-transferase P (GSTP1) | E.coli |
GSTP1 Proteins for Cricetulus longicaudatus (Long-tailed dwarf hamster) (Chinese hamster)
| Code | Product Name | Source |
|---|---|---|
| CSB-MP009989DXV CSB-EP009989DXV-B |
Recombinant Cricetulus longicaudatus Glutathione S-transferase P (GSTP1) | Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-BP009989DXV | Recombinant Cricetulus longicaudatus Glutathione S-transferase P (GSTP1) | Baculovirus |
| CSB-YP009989DXV | Recombinant Cricetulus longicaudatus Glutathione S-transferase P (GSTP1) | Yeast |
GSTP1 Proteins for Cricetulus migratorius (Gray dwarf hamster)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP009989CRY CSB-EP009989CRY CSB-BP009989CRY CSB-MP009989CRY CSB-EP009989CRY-B |
Recombinant Cricetulus migratorius Glutathione S-transferase P (GSTP1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
GSTP1 Proteins for Macaca mulatta (Rhesus macaque)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP634673MOW CSB-EP634673MOW CSB-BP634673MOW CSB-MP634673MOW CSB-EP634673MOW-B |
Recombinant Macaca mulatta Glutathione S-transferase P (GSTP1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
GSTP1 Proteins for Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP719183PYX CSB-EP719183PYX CSB-BP719183PYX CSB-MP719183PYX CSB-EP719183PYX-B |
Recombinant Pongo abelii Glutathione S-transferase P (GSTP1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
GSTP1 Proteins for Mesocricetus auratus (Golden hamster)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP723319MRG CSB-EP723319MRG CSB-BP723319MRG CSB-MP723319MRG CSB-EP723319MRG-B |
Recombinant Mesocricetus auratus Glutathione S-transferase P (GSTP1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
GSTP1 Proteins for Xenopus laevis (African clawed frog)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP818288XBE CSB-EP818288XBE CSB-BP818288XBE CSB-MP818288XBE CSB-EP818288XBE-B |
Recombinant Xenopus laevis Glutathione S-transferase P 1 (gstp1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
GSTP1 Proteins for Capra hircus (Goat)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP866140GO CSB-EP866140GO CSB-BP866140GO CSB-MP866140GO CSB-EP866140GO-B |
Recombinant Goat Glutathione S-transferase P (GSTP1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
GSTP1 Proteins for Cricetulus longicaudatus(Long-tailed dwarf hamster)(Chinese hamster)
| Code | Product Name | Source |
|---|---|---|
| CSB-EP009989DXV | Recombinant Cricetulus longicaudatus Glutathione S-transferase P (GSTP1) | E.coli |
GSTP1 ELISA Kit for Homo sapiens (Human)
| Code | Product Name | Sample Types | Sensitivity |
|---|---|---|---|
| CSB-E09032h | Human glutathione S-transferases,GSTpi ELISA Kit | serum, plasma, cell supernates, tissue homogenates | 0.39 ng/mL |