JAG2, also known as Jagged Canonical Notch Ligand 2, is a protein coding gene that encodes a ligand for the Notch signaling pathway. This pathway is crucial for embryonic development and cell fate decisions. JAG2 interacts with NOTCH2 and is regulated by microRNA miR-1280. It is involved in limb development and is associated with diseases such as muscular dystrophy and limb-girdle syndrome. JAG2 has been targeted in drug development for various conditions, including cancer and immune disorders.
Validated Data
The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using CSB-PA049990(JAG2 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: ×200)
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA049990(JAG2 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: ×200)
The following JAG2 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
JAG2 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA049990 | JAG2 Antibody | Human | ELISA,IHC |
JAG2 Proteins for Rattus norvegicus (Rat)
Code | Product Name | Source |
---|---|---|
CSB-YP011928RA CSB-EP011928RA CSB-BP011928RA CSB-MP011928RA CSB-EP011928RA-B |
Recombinant Rat Protein jagged-2 (Jag2), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
JAG2 Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
---|---|---|
CSB-YP879455MO CSB-EP879455MO CSB-BP879455MO CSB-MP879455MO CSB-EP879455MO-B |
Recombinant Mouse Protein jagged-2 (Jag2), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |