LY6G6D (Lymphocyte antigen 6 complex, locus G6D) is a transmembrane protein belonging to the LY6 family, mainly expressed in immune cells including macrophages, dendritic cells, NK cells, T cells, and B cells. The protein is usually expressed as an activation marker and participates in the immune response by regulating the activity and function of immune cells. Recent studies have shown that the expression level of LY6G6D is elevated in some cancers and is associated with increased proliferation and metastasis of cancer cells. For example, high expression of LY6G6D is associated with poor prognosis in cancers such as breast cancer, gastric cancer, and liver cancer. Therefore, LY6G6D has become an important target in cancer therapy. Some studies have suggested that by regulating the expression and activity of LY6G6D, it is possible to inhibit tumor cell proliferation and metastasis, thus improving treatment outcomes. Therefore, investigating the mechanism of action of LY6G6D and its potential as a therapeutic target is of great significance.
● Recombinant Human Lymphocyte antigen 6 complex locus protein G6d(LY6G6D) (Active) CSB-YP013246HU
Validated Data
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Activity
Measured by its binding ability in a functional ELISA. Immobilized Human LY6G6D at 2 μg/mL can bind Anti-LY6G6D recombinant antibody (CSB-RA013246MA1HU), the EC50 is 2.816-3.741 ng/mL.
Validated Data
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Activity
Measured by its binding ability in a functional ELISA. Immobilized Macaca fascicularis LY6G6D at 2 μg/mL can bind Anti-LY6G6D recombinant antibody (CSB-RA013246MA1HU), the EC50 is 3.963-7.154 ng/mL.
● LY6G6D Recombinant Monoclonal Antibody CSB-RA013246MA1HU
Validated Data
The Binding Activity of LY6G6D with anti-LY6G6D antibody
Activity: Measured by its binding ability in a functional ELISA. Immobilized Macaca fascicularis LY6G6D(CSB-YP4607MOV) at 2 μg/mL can bind Anti-LY6G6D recombinant antibody, the EC50 is 3.963-7.154 ng/mL.
The Binding Activity of LY6G6D with anti-LY6G6D antibody
Activity: Measured by its binding ability in a functional ELISA. Immobilized Human LY6G6D(CSB-YP013246HU) at 2 μg/mL can bind Anti-LY6G6D recombinant antibody, the EC50 is 2.816-3.741 ng/mL.
Untransfected HEK293T cells (green line) and transfected Human LY6G6D HEK293T stable cells (red line) were stained with anti-LY6G6D antibody (CSB-RA013246MA1HU) (2µg/1*106cells), washed and then followed by FITC-conjugated anti-Human IgG Fc antibody and analyzed with flow cytometry.
● CT26/Human LY6G6D Stable Cell Line CSB-SC013246HU
Validated Data
Untransfected CT26 cells (green line) and transfected Human LY6G6D CT26 stable cells (red line) were stained with anti-LY6G6D antibody (CSB-RA013246MA1HU) (2µg/1*106cells), washed and then followed by FITC-conjugated anti-Human IgG Fc antibody and analyzed with flow cytometry.
● HEK293T/Human LY6G6D Stable Cell Line CSB-SC013246HU2
Validated Data
Untransfected HEK293T cells (green line) and transfected Human LY6G6D HEK293T stable cells (red line) were stained with anti-LY6G6D antibody (CSB-RA013246MA1HU) (2µg/1*106cells), washed and then followed by FITC-conjugated anti-Human IgG Fc antibody and analyzed with flow cytometry.
The following LY6G6D reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
LY6G6D Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA013246ZA01HU | LY6G6D Antibody |
Homo sapiens | ELISA, WB (ensure identification of antigen) |
CSB-RA013246MA1HU | LY6G6D Recombinant Monoclonal Antibody |
Human, Macaca fascicularis | ELISA, FC |
LY6G6D Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP013246HU | Recombinant Human Lymphocyte antigen 6 complex locus protein G6d (LY6G6D) (Active) |
Yeast |
CSB-EP013246HU | Recombinant Human Lymphocyte antigen 6 complex locus protein G6d (LY6G6D) |
E.coli |
CSB-BP013246HU CSB-MP013246HU CSB-EP013246HU-B |
Recombinant Human Lymphocyte antigen 6 complex locus protein G6d (LY6G6D) |
Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-EP013246HU1 | Recombinant Human Lymphocyte antigen 6 complex locus protein G6d (LY6G6D), partial |
E.coli |
CSB-YP013246HU1 | Recombinant Human Lymphocyte antigen 6 complex locus protein G6d (LY6G6D), partial |
Yeast |
LY6G6D Proteins for Rattus norvegicus (Rat)
Code | Product Name | Source |
---|---|---|
CSB-EP750592RA CSB-BP750592RA CSB-MP750592RA CSB-EP750592RA-B |
Recombinant Rat Lymphocyte antigen 6 complex locus protein G6d (Ly6g6d) |
E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |