Membrane-bound transcription factor site-1 protease is a protein in humans that is encoded by MBTPS1 gene. Serine protease that catalyzes the first step in the proteolytic activation of the sterol regulatory element-binding proteins (SREBPs). Other known substrates are BDNF, GNPTAB and ATF6. Cleaves after hydrophobic or small residues, provided that Arg or Lys is in position P4. Cleaves known substrates after Arg-Ser-Val-Leu (SERBP-2), Arg-His-Leu-Leu (ATF6), Arg-Gly-Leu-Thr (BDNF) and its own propeptide after Arg-Arg-Leu-Leu. Mediates the protein cleavage of GNPTAB into subunit alpha and beta, thereby participating in biogenesis of lysosomes.
The following MBTPS1 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
MBTPS1 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA237035 | MBTPS1 Antibody |
Human,Mouse,Rat | ELISA,WB |
CSB-PA070134 | MBTPS1 Antibody |
Human,Mouse,Rat | WB, ELISA |
CSB-PA237035ESR1HU | MBTPS1 Antibody |
Human | ELISA, IHC |
CSB-PA237035ESR2HU | MBTPS1 Antibody |
Human | ELISA, IHC |
CSB-PA617930LA01HU | MBTPS1 Antibody |
Human | ELISA, IHC |
CSB-PA617930LA11HU | MBTPS1 Antibody |
Human | ELISA, IF |
CSB-PA617930LD01HU | MBTPS1 Antibody, Biotin conjugated |
Human | ELISA |
CSB-PA617930LD11HU | MBTPS1 Antibody, Biotin conjugated |
Human | ELISA |
CSB-PA617930LC01HU | MBTPS1 Antibody, FITC conjugated |
Human | |
CSB-PA617930LC11HU | MBTPS1 Antibody, FITC conjugated |
Human | |
CSB-MA617930A0m | MBTPS1 Monoclonal Antibody |
Human | ELISA, WB, FC |
MBTPS1 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP617930HU CSB-BP617930HU CSB-MP617930HU CSB-EP617930HU-B |
Recombinant Human Membrane-bound transcription factor site-1 protease (MBTPS1), partial |
Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-EP617930HU | Recombinant Human Membrane-bound transcription factor site-1 protease (MBTPS1), partial |
E.coli |
MBTPS1 Proteins for Rattus norvegicus (Rat)
Code | Product Name | Source |
---|---|---|
CSB-YP893411RA CSB-EP893411RA CSB-BP893411RA CSB-MP893411RA CSB-EP893411RA-B |
Recombinant Rat Membrane-bound transcription factor site-1 protease (Mbtps1), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
MBTPS1 Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
---|---|---|
CSB-YP895279MO CSB-EP895279MO CSB-BP895279MO CSB-MP895279MO CSB-EP895279MO-B |
Recombinant Mouse Membrane-bound transcription factor site-1 protease (Mbtps1), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |