Nuclear receptor coactivator 1 is a protein in humans that is encoded by NCOA1 gene. Nuclear receptor coactivator that directly binds nuclear receptors and stimulates the transcriptional activities in a hormone-dependent fashion. Involved in the coactivation of different nuclear receptors, such as for steroids (PGR, GR and ER), retinoids (RXRs), thyroid hormone (TRs) and prostanoids (PPARs). Also involved in coactivation mediated by STAT3, STAT5A, STAT5B and STAT6 transcription factors. Displays histone acetyltransferase activity toward H3 and H4; the relevance of such activity remains however unclear. Plays a central role in creating multisubunit coactivator complexes that act via remodeling of chromatin, and possibly acts by participating in both chromatin remodeling and recruitment of general transcription factors. Required with NCOA2 to control energy balance between white and brown adipose tissues.
The following NCOA1 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
NCOA1 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA015539GA01HU | NCOA1 Antibody |
Human | ELISA,WB |
CSB-PA015539HA01HU | NCOA1 Antibody |
Human | ELISA, IHC |
CSB-PA015539HB01HU | NCOA1 Antibody, HRP conjugated |
Human | ELISA |
CSB-PA015539HC01HU | NCOA1 Antibody, FITC conjugated |
Human | |
CSB-PA015539HD01HU | NCOA1 Antibody, Biotin conjugated |
Human | ELISA |
NCOA1 Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
---|---|---|
CSB-YP015539MO CSB-EP015539MO CSB-BP015539MO CSB-MP015539MO CSB-EP015539MO-B |
Recombinant Mouse Nuclear receptor coactivator 1 (Ncoa1), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
NCOA1 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP015539HU CSB-EP015539HU CSB-BP015539HU CSB-MP015539HU CSB-EP015539HU-B |
Recombinant Human Nuclear receptor coactivator 1 (NCOA1), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
NCOA1 Proteins for Sus scrofa (Pig)
Code | Product Name | Source |
---|---|---|
CSB-YP015539PI CSB-EP015539PI CSB-BP015539PI CSB-MP015539PI CSB-EP015539PI-B |
Recombinant Pig Nuclear receptor coactivator 1 (NCOA1), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |