Nectin-3 is a protein in humans that is encoded by NECTIN3 gene. Plays a role in cell-cell adhesion through heterophilic trans-interactions with nectin-like proteins or nectins, such as trans-interaction with NECTIN2 at Sertoli-spermatid junctions. Trans-interaction with PVR induces activation of CDC42 and RAC small G proteins through common signaling molecules such as SRC and RAP1. Also involved in the formation of cell-cell junctions, including adherens junctions and synapses. Induces endocytosis-mediated down-regulation of PVR from the cell surface, resulting in reduction of cell movement and proliferation. Plays a role in the morphology of the ciliary body.
The following NECTIN3 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
NECTIN3 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA019097GA01HU | PVRL3 Antibody |
Human,Mouse,Rat | ELISA,WB,IHC |
CSB-PA003390 | PVRL3 Antibody |
Human,Mouse | WB, ELISA |
CSB-PA005242 | PVRL3 Antibody |
Human,Mouse,Rat | WB, ELISA |
CSB-PA250008 | PVRL3 Antibody |
Human,Mouse | ELISA,IHC |
CSB-PA520187 | PVRL3 Antibody |
Human,Mouse | ELISA,WB,IHC |
CSB-PA882076ESR2HU | NECTIN3 Antibody |
Human | ELISA, IHC |
NECTIN3 Antibodies for Danio rerio (Zebrafish) (Brachydanio rerio)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA691314XA01DIL | nectin3 Antibody |
Danio rerio (Zebrafish) (Brachydanio rerio) | ELISA, WB (ensure identification of antigen) |
NECTIN3 Proteins for Danio rerio (Zebrafish) (Brachydanio rerio)
Code | Product Name | Source |
---|---|---|
CSB-YP691314DIL CSB-EP691314DIL CSB-BP691314DIL CSB-MP691314DIL CSB-EP691314DIL-B |
Recombinant Danio rerio Poliovirus receptor-related protein 3-like (pvrl3l), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
NECTIN3 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP882076HU | Recombinant Human Poliovirus receptor-related protein 3 (PVRL3), partial,Yeast |
Yeast |
CSB-EP882076HU CSB-BP882076HU CSB-MP882076HU CSB-EP882076HU-B |
Recombinant Human Poliovirus receptor-related protein 3 (PVRL3), partial |
E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
NECTIN3 Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
---|---|---|
CSB-YP888348MO CSB-EP888348MO CSB-BP888348MO CSB-MP888348MO CSB-EP888348MO-B |
Recombinant Mouse Poliovirus receptor-related protein 3 (Pvrl3), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |