NEFL

NEFL stands for Neurofilament Light, a protein constituting part of the neuronal cell's cytoskeleton, playing a significant role in the nervous system. It contributes to maintaining the structure and morphology of neurons. As a cytoskeletal protein, NEFL plays a critical role in supporting the shape and stability of neurons. Variations or abnormal expression levels of NEFL are associated with neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS) and peripheral neuropathies. Assessing NEFL levels allows for the evaluation of the severity of neurodegenerative diseases and might serve as a biomarker aiding in diagnosis and monitoring disease progression.

Popular Product:

Recombinant Human Neurofilament light polypeptide (NEFL)

Validated Data

SDS-PAGE

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

LC-MS/MS

Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-EP015688HU could indicate that this peptide derived from E.coli-expressed Homo sapiens (Human) NEFL.

LC-MS/MS

Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-EP015688HU could indicate that this peptide derived from E.coli-expressed Homo sapiens (Human) NEFL.