NTN1, also known as Netrin-1, is a protein composed of an α-helical structure and encoded by the NTN1 gene. This protein plays a crucial role in the development of neurons. NTN1 guides the growth of neuronal axons and the formation of synapses by recognizing and binding to its receptors. This binding often depends on the presence of Ca2+ ions, which activates endogenous signaling pathways through the receptor, ultimately affecting neuronal development and function. Additionally, Netrin-1 can inhibit the apoptosis (cell death) of tumor cells, promote the formation of new blood vessels, and regulate fibroblasts. Netrin-1 is also involved in the epithelial-mesenchymal transition (EMT) process, which is closely related to tumorigenesis, progression, metastasis, and drug resistance. Blocking Netrin-1 can inhibit the EMT process, thereby exerting a significant impact on tumor development.
Recombinant Human Netrin-1 (NTN1)
Source: Yeast
Source: E.coli
Source: Baculovirus
Source: Mammalian cell
Source: In Vivo Biotinylation in E.coli
The following NTN1 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
NTN1 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA003404 | NTN1 Antibody |
Human,Mouse,Rat,Monkey | WB, IHC, ELISA |
CSB-PA006035 | NTN1 Antibody |
Human,Mouse,Rat | WB, ELISA |
CSB-PA016127LA01HU | NTN1 Antibody |
Human | ELISA, WB, IHC |
CSB-PA016127LC01HU | NTN1 Antibody, FITC conjugated |
Human | |
CSB-PA016127LD01HU | NTN1 Antibody, Biotin conjugated |
Human | ELISA |
NTN1 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP016127HU CSB-EP016127HU CSB-BP016127HU CSB-MP016127HU CSB-EP016127HU-B |
Recombinant Human Netrin-1 (NTN1) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
NTN1 ELISA Kit for Homo sapiens (Human)
Code | Product Name | Sample Types | Sensitivity |
---|---|---|---|
CSB-E11899h | Human Netrin-1,Ntn1 ELISA Kit |
serum, plasma, cell culture supernates | 7.81 pg/mL |