Serine/threonine-protein kinase PAK 1 is a protein in humans that is encoded by PAK1 gene. Protein kinase involved in intracellular signaling pathways downstream of integrins and receptor-type kinases that plays an important role in cytoskeleton dynamics, in cell adhesion, migration, proliferation, apoptosis, mitosis, and in vesicle-mediated transport processes. Can directly phosphorylate BAD and protects cells against apoptosis. Activated by interaction with CDC42 and RAC1. Functions as GTPase effector that links the Rho-related GTPases CDC42 and RAC1 to the JNK MAP kinase pathway. Phosphorylates and activates MAP2K1, and thereby mediates activation of downstream MAP kinases. Involved in the reorganization of the actin cytoskeleton, actin stress fibers and of focal adhesion complexes. Phosphorylates the tubulin chaperone TBCB and thereby plays a role in the regulation of microtubule biogenesis and organization of the tubulin cytoskeleton.
The following PAK1 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
PAK1 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA017404GA01HU | PAK1 Antibody |
Human | ELISA,WB,IHC |
CSB-PA613382DSR1HU | PAK1 Antibody |
Human | ELISA, IHC |
CSB-PA077904 | Phospho-PAK1 (Thr212) Antibody |
Human,Mouse,Rat | ELISA,WB,IHC,IF |
CSB-PA069102 | Phospho-PAK1/PAK2/PAK3 (Thr423/Thr402/Thr421) Antibody |
Human,Mouse,Rat | ELISA,IHC,IF |
CSB-PA861105 | PAK1 (Ab-212) Antibody |
Human,Mouse,Rat | ELISA,WB,IHC,IF |
CSB-PA583804 | PAK1/PAK2/PAK3 (Ab-423/402/421) Antibody |
Human,Mouse,Rat | ELISA,WB,IHC,IF |
CSB-PA199192 | Phospho-PAK1 (Ser199) Antibody |
Human,Mouse,Rat | ELISA,WB,IHC |
CSB-PA294797 | Phospho-PAK1 (Ser204) Antibody |
Human,Mouse,Rat | ELISA,WB,IHC |
CSB-PA089760 | PAK1/PAK2/PAK3 (Ab-423/402/421) Antibody |
Human,Mouse,Rat | ELISA,WB,IHC |
CSB-PA036079 | PAK1 (Ab-199) Antibody |
Human,Mouse,Rat | ELISA,WB,IHC |
CSB-PA900649 | PAK1 (Ab-204) Antibody |
Human,Mouse | ELISA,WB,IHC |
CSB-PA003703 | PAK1 Antibody |
Human,Mouse,Rat | WB, IHC, IF, ELISA |
CSB-PA020203 | Phospho-PAK1 (T212) Antibody |
Human,Mouse,Rat | WB, IHC, ELISA |
CSB-PA020204 | Phospho-PAK1 (S199) Antibody |
Human,Mouse,Rat,Monkey | WB, IHC, ELISA |
CSB-PA020205 | Phospho-PAK1 (S204) Antibody |
Human,Mouse,Rat | WB, IHC, ELISA |
CSB-PA020206 | PAK1 Antibody |
Human,Mouse,Rat | WB, IHC, IF, ELISA |
CSB-PA020209 | PAK1 Antibody |
Human,Mouse,Rat | WB, IHC, ELISA |
CSB-PA238998 | PAK1 Antibody |
Human,Mouse,Rat | ELISA,WB,IHC |
CSB-PA116147 | PAK1 Antibody |
Human,Mouse,Rat | ELISA,WB,IHC |
CSB-RA287160A0HU | PAK1 Recombinant Monoclonal Antibody |
Human, Mouse | ELISA, WB, IF |
PAK1 Proteins for Rattus norvegicus (Rat)
Code | Product Name | Source |
---|---|---|
CSB-YP017404RA CSB-EP017404RA CSB-BP017404RA CSB-MP017404RA CSB-EP017404RA-B |
Recombinant Rat Serine/threonine-protein kinase PAK 1 (Pak1) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PAK1 Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
---|---|---|
CSB-YP017404MO CSB-EP017404MO CSB-BP017404MO CSB-MP017404MO CSB-EP017404MO-B |
Recombinant Mouse Serine/threonine-protein kinase PAK 1 (Pak1) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PAK1 Proteins for Bos taurus (Bovine)
Code | Product Name | Source |
---|---|---|
CSB-YP600957BO CSB-EP600957BO CSB-BP600957BO CSB-MP600957BO CSB-EP600957BO-B |
Recombinant Bovine Serine/threonine-protein kinase PAK 1 (PAK1), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PAK1 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP613382HU CSB-BP613382HU CSB-MP613382HU CSB-EP613382HU-B |
Recombinant Human Serine/threonine-protein kinase PAK 1 (PAK1) |
Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-EP613382HU | Recombinant Human Serine/threonine-protein kinase PAK 1 (PAK1) |
E.coli |