PAK1 Research Reagents

Serine/threonine-protein kinase PAK 1 is a protein in humans that is encoded by PAK1 gene. Protein kinase involved in intracellular signaling pathways downstream of integrins and receptor-type kinases that plays an important role in cytoskeleton dynamics, in cell adhesion, migration, proliferation, apoptosis, mitosis, and in vesicle-mediated transport processes. Can directly phosphorylate BAD and protects cells against apoptosis. Activated by interaction with CDC42 and RAC1. Functions as GTPase effector that links the Rho-related GTPases CDC42 and RAC1 to the JNK MAP kinase pathway. Phosphorylates and activates MAP2K1, and thereby mediates activation of downstream MAP kinases. Involved in the reorganization of the actin cytoskeleton, actin stress fibers and of focal adhesion complexes. Phosphorylates the tubulin chaperone TBCB and thereby plays a role in the regulation of microtubule biogenesis and organization of the tubulin cytoskeleton.

The following PAK1 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

PAK1 Antibodies

PAK1 Antibodies for Homo sapiens (Human)

PAK1 Proteins

PAK1 Proteins for Rattus norvegicus (Rat)

PAK1 Proteins for Mus musculus (Mouse)

PAK1 Proteins for Bos taurus (Bovine)

PAK1 Proteins for Homo sapiens (Human)

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