Cardiac phospholamban is a protein in humans that is encoded by PLN gene. Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. ATP2A2 inhibition is alleviated by PLN phosphorylation.
The following PLN reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
PLN Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA030090 | Phospho-PLN (S16/T17) Antibody | Human,Mouse,Rat | IF, ELISA |
CSB-PA030091 | PLN Antibody | Human,Mouse,Rat | IF, ELISA |
CSB-PA018198LA01HU | PLN Antibody | Human | ELISA, IHC |
CSB-PA018198LD01HU | PLN Antibody, Biotin conjugated | Human | ELISA |
CSB-PA018198LC01HU | PLN Antibody, FITC conjugated | Human |
PLN Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP018198HU | Recombinant Human Cardiac phospholamban (PLN) | Yeast |
CSB-EP018198HU CSB-BP018198HU CSB-MP018198HU CSB-EP018198HU-B |
Recombinant Human Cardiac phospholamban (PLN) | E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PLN Proteins for Gallus gallus (Chicken)
Code | Product Name | Source |
---|---|---|
CSB-YP018198CH CSB-EP018198CH CSB-BP018198CH CSB-MP018198CH CSB-EP018198CH-B |
Recombinant Chicken Cardiac phospholamban (PLN), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PLN Proteins for Canis lupus familiaris (Dog) (Canis familiaris)
Code | Product Name | Source |
---|---|---|
CSB-YP018198DO CSB-EP018198DO CSB-BP018198DO CSB-MP018198DO CSB-EP018198DO-B |
Recombinant Dog Cardiac phospholamban (PLN), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PLN Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
---|---|---|
CSB-YP018198MO CSB-EP018198MO CSB-BP018198MO CSB-MP018198MO CSB-EP018198MO-B |
Recombinant Mouse Cardiac phospholamban (Pln), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PLN Proteins for Oryctolagus cuniculus (Rabbit)
Code | Product Name | Source |
---|---|---|
CSB-YP018198RB CSB-EP018198RB CSB-BP018198RB CSB-MP018198RB CSB-EP018198RB-B |
Recombinant Rabbit Cardiac phospholamban (PLN), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PLN Proteins for Sus scrofa (Pig)
Code | Product Name | Source |
---|---|---|
CSB-YP018198PI CSB-EP018198PI CSB-BP018198PI CSB-MP018198PI CSB-EP018198PI-B |
Recombinant Pig Cardiac phospholamban (PLN), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PLN Proteins for Bos taurus (Bovine)
Code | Product Name | Source |
---|---|---|
CSB-YP018198BO CSB-EP018198BO CSB-BP018198BO CSB-MP018198BO CSB-EP018198BO-B |
Recombinant Bovine Cardiac phospholamban (PLN), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PLN Proteins for Rattus norvegicus (Rat)
Code | Product Name | Source |
---|---|---|
CSB-YP018198RA CSB-EP018198RA CSB-BP018198RA CSB-MP018198RA CSB-EP018198RA-B |
Recombinant Rat Cardiac phospholamban (Pln), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PLN Proteins for Pichia angusta (Yeast) (Hansenula polymorpha)
Code | Product Name | Source |
---|---|---|
CSB-YP647283EVQ CSB-EP647283EVQ CSB-BP647283EVQ CSB-MP647283EVQ CSB-EP647283EVQ-B |
Recombinant Pichia angusta Lon protease homolog 2, peroxisomal (PLN), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |