PLTP

Phospholipid Transfer Protein (PLTP), also referred to as lipid transfer protein, mediates phospholipid exchange between lipoproteins and cell membranes. It remodels high-density lipoprotein (HDL) particles, facilitating cholesterol efflux from peripheral cells and supporting reverse cholesterol transport (RCT), a critical pathway for lipid homeostasis.
PLTP interacts with lipid metabolism pathways like HDL maturation and cholesterol trafficking. Its dysregulation correlates with atherosclerosis, coronary artery disease, and metabolic syndrome. Preclinical research is investigating PLTP inhibitors to optimize lipid profiles, targeting enhanced HDL function to reduce cardiovascular risk, though no such agents have advanced to clinical trials.

Validated Data

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

PLTP Antibody (CSB-PA018212EA01HU)

Validated Data

IHC image of CSB-PA018212EA01HU diluted at 1:200 and staining in paraffin-embedded human testis tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

IHC image of CSB-PA018212EA01HU diluted at 1:200 and staining in paraffin-embedded human appendix tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

Human phospholipid transfer protein(PLTP)Elisa Kit (CSB-E12838h)

Validated Data

Code: CSB-E12838h

Size: 96T,5×96T,10×96T

Sensitivity: 0.58 ng/mL

Detection Range: 2.34 ng/mL-150 ng/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

The following PLTP reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

PLTP Antibodies

PLTP Proteins

PLTP ELISA Kits

PLTP Antibodies

PLTP Antibodies for Homo sapiens (Human)

Code	Product Name	Species Reactivity	Application
CSB-PA018212EA01HU	PLTP Antibody	Human	ELISA, IHC
CSB-PA253412	PLTP Antibody	Human,Mouse	ELISA,WB

PLTP Proteins

PLTP Proteins for Homo sapiens (Human)

Code	Product Name	Source
CSB-EP018212HU	Recombinant Human Phospholipid transfer protein (PLTP)	E.coli
CSB-BP018212HU CSB-MP018212HU CSB-EP018212HU-B	Recombinant Human Phospholipid transfer protein (PLTP)	Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-YP018212HU(F2)	Recombinant Human Phospholipid transfer protein (PLTP)	Yeast

PLTP Proteins for Mus musculus (Mouse)

Code	Product Name	Source
CSB-YP018212MO CSB-BP018212MO CSB-EP018212MO-B	Recombinant Mouse Phospholipid transfer protein (Pltp)	Yeast Baculovirus In Vivo Biotinylation in E.coli

PLTP Proteins for Aspergillus oryzae (strain ATCC 42149 / RIB 40) (Yellow koji mold)

Code	Product Name	Source
CSB-YP529635DPA CSB-EP529635DPA CSB-BP529635DPA CSB-MP529635DPA CSB-EP529635DPA-B	Recombinant Aspergillus oryzae Phosphatidylglycerol/phosphatidylinositol transfer protein (pltp)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

PLTP ELISA Kit

PLTP ELISA Kit for Homo sapiens (Human)

Code	Product Name	Sample Types	Sensitivity
CSB-E12838h	Human phospholipid transfer protein(PLTP)Elisa Kit	serum, plasma, tissue homogenates	0.58 ng/mL

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PLTP

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