POU2F1

POU2F1, also known as Oct - 1, is a protein encoded by the POU2F1 gene. It belongs to the POU - domain transcription factor family. Oct - 1 regulates gene expression by binding to specific DNA sequences, influencing multiple biological processes such as cell cycle regulation and differentiation. It is involved in several signaling pathways, including the Wnt and Notch pathways.
Mutations or dysregulation of POU2F1 have been associated with various diseases, such as some types of cancers and neurological disorders. In drug development, targeting POU2F1 is considered a potential strategy, although significant challenges remain in terms of specificity and efficacy. Research is ongoing to better understand its role and develop more effective therapies.