PRKCI Research Reagents

Protein kinase C iota type is a protein in humans that is encoded by PRKCI gene. Calcium- and diacylglycerol-independent serine/ threonine-protein kinase that plays a general protective role against apoptotic stimuli, is involved in NF-kappa-B activation, cell survival, differentiation and polarity, and contributes to the regulation of microtubule dynamics in the early secretory pathway. Is necessary for BCR-ABL oncogene-mediated resistance to apoptotic drug in leukemia cells, protecting leukemia cells against drug-induced apoptosis. In cultured neurons, prevents amyloid beta protein-induced apoptosis by interrupting cell death process at a very early step. In glioblastoma cells, may function downstream of phosphatidylinositol 3-kinase (PI(3)K) and PDPK1 in the promotion of cell survival by phosphorylating and inhibiting the pro-apoptotic factor BAD.

The following PRKCI reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

PRKCI Antibodies

PRKCI Antibodies for Homo sapiens (Human)

PRKCI Antibodies for Danio rerio (Zebrafish) (Brachydanio rerio)

PRKCI Proteins

PRKCI Proteins for Homo sapiens (Human)

PRKCI Proteins for Rattus norvegicus (Rat)

PRKCI Proteins for Mus musculus (Mouse)

PRKCI Proteins for Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)

PRKCI Proteins for Danio rerio (Zebrafish) (Brachydanio rerio)

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