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Proteasome activator complex subunit 3 is a protein in humans that is encoded by PSME3 gene. Subunit of the 11S REG-gamma (also called PA28-gamma) proteasome regulator, a doughnut-shaped homoheptamer which associates with the proteasome. 11S REG-gamma activates the trypsin-like catalytic subunit of the proteasome but inhibits the chymotrypsin-like and postglutamyl-preferring (PGPH) subunits. Facilitates the MDM2-p53/TP53 interaction which promotes ubiquitination- and MDM2-dependent proteasomal degradation of p53/TP53, limiting its accumulation and resulting in inhibited apoptosis after DNA damage. May also be involved in cell cycle regulation.
The following PSME3 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
PSME3 Antibodies for Homo sapiens (Human)
| Code | Product Name | Species Reactivity | Application |
|---|---|---|---|
| CSB-PA018918GA01HU | PSME3 Antibody |
Human,Mouse,Rat | ELISA,WB,IHC,IF |
| CSB-PA13674A0Rb | PSME3 Antibody |
Human | ELISA, IHC, IF |
PSME3 Proteins for Sus scrofa (Pig)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP018918PI CSB-EP018918PI CSB-BP018918PI CSB-MP018918PI CSB-EP018918PI-B |
Recombinant Pig Proteasome activator complex subunit 3 (PSME3) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PSME3 Proteins for Homo sapiens (Human)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP018918HU CSB-BP018918HU CSB-MP018918HU CSB-EP018918HU-B |
Recombinant Human Proteasome activator complex subunit 3 (PSME3) |
Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP018918HU1 | Recombinant Human Proteasome activator complex subunit 3 (PSME3), partial |
E.coli |
PSME3 Proteins for Mus musculus (Mouse)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP018918MO CSB-EP018918MO CSB-BP018918MO CSB-MP018918MO CSB-EP018918MO-B |
Recombinant Mouse Proteasome activator complex subunit 3 (Psme3) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PSME3 Proteins for Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP700141MOV CSB-EP700141MOV CSB-BP700141MOV CSB-MP700141MOV CSB-EP700141MOV-B |
Recombinant Macaca fascicularis Proteasome activator complex subunit 3 (PSME3) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PSME3 Proteins for Gallus gallus (Chicken)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP707861CH CSB-EP707861CH CSB-BP707861CH CSB-MP707861CH CSB-EP707861CH-B |
Recombinant Chicken Proteasome activator complex subunit 3 (PSME3) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PSME3 Proteins for Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP722465PYX CSB-EP722465PYX CSB-BP722465PYX CSB-MP722465PYX CSB-EP722465PYX-B |
Recombinant Pongo abelii Proteasome activator complex subunit 3 (PSME3) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PSME3 Proteins for Dictyostelium discoideum (Slime mold)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP836163DKK CSB-EP836163DKK CSB-BP836163DKK CSB-MP836163DKK CSB-EP836163DKK-B |
Recombinant Dictyostelium discoideum Proteasome activator 28 (psmE3) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
