QPCT, full name glutaminyl-peptide cyclotransferase, also known as peptidyl cyclase T. It is a protein-modifying enzyme regulating protein structure and function via glutaminyl cyclization, participating in signal transduction and tumor progression. Abnormal QPCT overexpression promotes tumor proliferation, metastasis and immune escape in multiple cancers. QPCT inhibitors are under preclinical research for anti-tumor therapy.
Recombinant Human Glutaminyl-peptide cyclotransferase (QPCT) (CSB-BP019135HU)
Validated Data
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
QPCT Antibody (CSB-PA019135LA01HU)
Validated Data
Western Blot
Positive WB detected in: HepG2 whole cell lysate(30µg), COLO205 whole cell lysate(30µg), MCF7 whole cell lysate(30µg), A431 whole cell lysate(20µg), Hela whole cell lysate(30µg)
All lanes: QPCT antibody at 1:1000
Secondary
Goat polyclonal to rabbit IgG at 1/40000 dilution
Predicted band size: 41,36 kDa
Observed band size: 41 kDa
Exposure time: 120s
Western Blot
Positive WB detected in: Rat Brain tissue lysate(30µg),Rat Stomach tissue lysate(30µg)
All lanes: QPCT antibody at 1:1000
Secondary
Goat polyclonal to rabbit IgG at 1/40000 dilution
Predicted band size: 41,36 kDa
Observed band size: 41 kDa
Exposure time: 120s
Human Glutaminyl-peptide cyclotransferase(QPCT) ELISA kit (CSB-EL019135HU)
Validated Data
Code: CSB-EL019135HU
Size: 96T,5×96T,10×96T
Sensitivity: 0.078 ng/mL
Detection Range: 0.312 ng/mL-20 ng/mL
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
The following QPCT reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
QPCT Antibodies for Homo sapiens (Human)
| Code | Product Name | Species Reactivity | Application |
|---|---|---|---|
| CSB-PA019135LC01HU | QPCT Antibody, FITC conjugated | Human | |
| CSB-PA019135LA01HU | QPCT Antibody | Human, Rat | ELISA, WB |
QPCT Proteins for Homo sapiens (Human)
| Code | Product Name | Source |
|---|---|---|
| CSB-EP019135HU-B |
Recombinant Human Glutaminyl-peptide cyclotransferase (QPCT) | In Vivo Biotinylation in E.coli |
| CSB-EP019135HU | Recombinant Human Glutaminyl-peptide cyclotransferase (QPCT) | E.coli |
| CSB-YP019135HU | Recombinant Human Glutaminyl-peptide cyclotransferase (QPCT) | Yeast |
| CSB-MP019135HU | Recombinant Human Glutaminyl-peptide cyclotransferase (QPCT) | Mammalian cell |
| CSB-BP019135HU | Recombinant Human Glutaminyl-peptide cyclotransferase (QPCT) | Baculovirus |
QPCT ELISA Kit for Homo sapiens (Human)
| Code | Product Name | Sample Types | Sensitivity |
|---|---|---|---|
| CSB-EL019135HU | Human Glutaminyl-peptide cyclotransferase(QPCT) ELISA kit | serum, plasma, tissue homogenates | 0.078 ng/mL |