REST

RE1-silencing transcription factor is a protein in humans that is encoded by REST gene. Transcriptional repressor which binds neuron-restrictive silencer element (NRSE) and represses neuronal gene transcription in non-neuronal cells. Restricts the expression of neuronal genes by associating with two distinct corepressors, mSin3 and CoREST, which in turn recruit histone deacetylase to the promoters of REST-regulated genes. Mediates repression by recruiting the BHC complex at RE1/NRSE sites which acts by deacetylating and demethylating specific sites on histones, thereby acting as a chromatin modifier. Transcriptional repression by REST-CDYL via the recruitment of histone methyltransferase EHMT2 may be important in transformation suppression.

The following REST reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

REST Antibodies

REST Proteins

REST ELISA Kits

REST Antibodies

REST Antibodies for Homo sapiens (Human)

Code	Product Name	Species Reactivity	Application
CSB-PA049156	REST Antibody	Human	ELISA,WB
CSB-PA019571LA01HU	REST Antibody	Human	ELISA, IF
CSB-PA019571LB01HU	REST Antibody, HRP conjugated	Human	ELISA
CSB-PA019571LC01HU	REST Antibody, FITC conjugated	Human
CSB-PA019571LD01HU	REST Antibody, Biotin conjugated	Human	ELISA

REST Antibodies for Danio rerio (Zebrafish) (Brachydanio rerio)

Code	Product Name	Species Reactivity	Application
CSB-PA019571XA01DIL	rest Antibody	Danio rerio (Zebrafish) (Brachydanio rerio)	ELISA, WB (ensure identification of antigen)

REST Proteins

REST Proteins for Rattus norvegicus (Rat)

Code	Product Name	Source
CSB-YP019571RA CSB-EP019571RA CSB-BP019571RA CSB-MP019571RA CSB-EP019571RA-B	Recombinant Rat RE1-silencing transcription factor (Rest), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

REST Proteins for Borrelia burgdorferi (strain ATCC 35210 / B31 / CIP 102532 / DSM 4680)

Code	Product Name	Source
CSB-YP527441BUD CSB-EP527441BUD CSB-BP527441BUD CSB-MP527441BUD CSB-EP527441BUD-B	Recombinant Borrelia burgdorferi Telomere resolvase resT (resT)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

REST Proteins for Mus musculus (Mouse)

Code	Product Name	Source
CSB-YP019571MO CSB-EP019571MO CSB-BP019571MO CSB-MP019571MO CSB-EP019571MO-B	Recombinant Mouse RE1-silencing transcription factor (Rest), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

REST Proteins for Homo sapiens (Human)

Code	Product Name	Source
CSB-YP019571HU CSB-EP019571HU CSB-BP019571HU CSB-MP019571HU CSB-EP019571HU-B	Recombinant Human RE1-silencing transcription factor (REST), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

REST Proteins for Danio rerio (Zebrafish) (Brachydanio rerio)

Code	Product Name	Source
CSB-YP019571DIL CSB-EP019571DIL CSB-BP019571DIL CSB-MP019571DIL CSB-EP019571DIL-B	Recombinant Danio rerio RE1-silencing transcription factor (rest), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

REST ELISA Kit

REST ELISA Kit for Homo sapiens (Human)

Code	Product Name	Sample Types	Sensitivity
CSB-EL019571HU	Human RE1-silencing transcription factor(REST) ELISA kit	serum, plasma, tissue homogenates, cell lysates	7.81 pg/mL

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