REST Research Reagents

RE1-silencing transcription factor is a protein in humans that is encoded by REST gene. Transcriptional repressor which binds neuron-restrictive silencer element (NRSE) and represses neuronal gene transcription in non-neuronal cells. Restricts the expression of neuronal genes by associating with two distinct corepressors, mSin3 and CoREST, which in turn recruit histone deacetylase to the promoters of REST-regulated genes. Mediates repression by recruiting the BHC complex at RE1/NRSE sites which acts by deacetylating and demethylating specific sites on histones, thereby acting as a chromatin modifier. Transcriptional repression by REST-CDYL via the recruitment of histone methyltransferase EHMT2 may be important in transformation suppression.

The following REST reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

REST Antibodies

REST Antibodies for Homo sapiens (Human)

REST Antibodies for Danio rerio (Zebrafish) (Brachydanio rerio)

REST Proteins

REST Proteins for Rattus norvegicus (Rat)

REST Proteins for Borrelia burgdorferi (strain ATCC 35210 / B31 / CIP 102532 / DSM 4680)

REST Proteins for Mus musculus (Mouse)

REST Proteins for Homo sapiens (Human)

REST Proteins for Danio rerio (Zebrafish) (Brachydanio rerio)

REST ELISA Kit

REST ELISA Kit for Homo sapiens (Human)

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