SMAD4

Mothers against decapentaplegic homolog 4 is a protein in humans that is encoded by SMAD4 gene. In muscle physiology, plays a central role in the balance between atrophy and hypertrophy. When recruited by MSTN, promotes atrophy response via phosphorylated SMAD2/4. MSTN decrease causes SMAD4 release and subsequent recruitment by the BMP pathway to promote hypertrophy via phosphorylated SMAD1/5/8. Acts synergistically with SMAD1 and YY1 in bone morphogenetic protein (BMP)-mediated cardiac-specific gene expression. Binds to SMAD binding elements (SBEs) (5'-GTCT/AGAC-3') within BMP response element (BMPRE) of cardiac activating regions (By similarity). Common SMAD (co-SMAD) is the coactivator and mediator of signal transduction by TGF-beta (transforming growth factor). Component of the heterotrimeric SMAD2/SMAD3-SMAD4 complex that forms in the nucleus and is required for the TGF-mediated signaling.

SMAD4 Antibodies

SMAD4 Antibodies for Homo sapiens (Human)

Code Product Name Species Reactivity Application
CSB-PA021789GA01HU SMAD4 Antibody Human,Mouse,Rat ELISA,WB
CSB-PA825890 SMAD4 Antibody Human,Mouse,Rat ELISA,WB
CSB-PA619768GA01HU SMAD4 Antibody Human ELISA,WB,IHC
CSB-PA009961 SMAD4 Antibody Human,Mouse,Rat,Monkey WB,IHC,IF,ELISA
CSB-PA619768LA01HU SMAD4 Antibody Human ELISA, WB, IHC, IP
CSB-PA619768LB01HU SMAD4 Antibody, HRP conjugated Human ELISA
CSB-PA619768LC01HU SMAD4 Antibody, FITC conjugated Human ELISA
CSB-PA619768LD01HU SMAD4 Antibody, Biotin conjugated Human ELISA

SMAD4 Proteins

SMAD4 Proteins for Mus musculus (Mouse)

Code Product Name Source
CSB-YP021789MO Recombinant Mouse Mothers against decapentaplegic homolog 4(Smad4),Yeast Yeast
CSB-EP021789MO Recombinant Mouse Mothers against decapentaplegic homolog 4(Smad4),Escherichia Coli E.coli
CSB-BP021789MO Recombinant Mouse Mothers against decapentaplegic homolog 4(Smad4),Baculovirus Baculovirus
CSB-MP021789MO Recombinant Mouse Mothers against decapentaplegic homolog 4(Smad4),Mammalian cell Mammalian cell

SMAD4 Proteins for Rattus norvegicus (Rat)

Code Product Name Source
CSB-YP021789RA Recombinant Rat Mothers against decapentaplegic homolog 4(Smad4),Yeast Yeast
CSB-EP021789RA Recombinant Rat Mothers against decapentaplegic homolog 4(Smad4),Escherichia Coli E.coli
CSB-BP021789RA Recombinant Rat Mothers against decapentaplegic homolog 4(Smad4),Baculovirus Baculovirus
CSB-MP021789RA Recombinant Rat Mothers against decapentaplegic homolog 4(Smad4),Mammalian cell Mammalian cell

SMAD4 Proteins for Homo sapiens (Human)

Code Product Name Source
CSB-YP619768HU Recombinant Human Mothers against decapentaplegic homolog 4(SMAD4),Yeast Yeast
CSB-EP619768HU Recombinant Human Mothers against decapentaplegic homolog 4(SMAD4),Escherichia Coli E.coli
CSB-BP619768HU Recombinant Human Mothers against decapentaplegic homolog 4(SMAD4),Baculovirus Baculovirus
CSB-MP619768HU Recombinant Human Mothers against decapentaplegic homolog 4(SMAD4),Mammalian cell Mammalian cell

SMAD4 Proteins for Bos taurus (Bovine)

Code Product Name Source
CSB-YP627061BO Recombinant Bovine Mothers against decapentaplegic homolog 4(SMAD4) ,partial,Yeast Yeast
CSB-EP627061BO Recombinant Bovine Mothers against decapentaplegic homolog 4(SMAD4) ,partial,Escherichia Coli E.coli
CSB-BP627061BO Recombinant Bovine Mothers against decapentaplegic homolog 4(SMAD4) ,partial,Baculovirus Baculovirus
CSB-MP627061BO Recombinant Bovine Mothers against decapentaplegic homolog 4(SMAD4) ,partial,Mammalian cell Mammalian cell

SMAD4 Proteins for Sus scrofa (Pig)

Code Product Name Source
CSB-YP884388PI Recombinant Pig Mothers against decapentaplegic homolog 4(SMAD4) ,partial,Yeast Yeast
CSB-EP884388PI Recombinant Pig Mothers against decapentaplegic homolog 4(SMAD4) ,partial,Escherichia Coli E.coli
CSB-BP884388PI Recombinant Pig Mothers against decapentaplegic homolog 4(SMAD4) ,partial,Baculovirus Baculovirus
CSB-MP884388PI Recombinant Pig Mothers against decapentaplegic homolog 4(SMAD4) ,partial,Mammalian cell Mammalian cell

SMAD4 cDNA

SMAD4 cDNA for Homo sapiens (Human)

Code Product Name Vector Accession NO.
CSB-CL619768HU1 SMAD4 pUC NM_005359.5

SMAD4 cDNA for Bos taurus (Bovine)

Code Product Name Vector Accession NO.
CSB-CL627061BO SMAD4 pUC NM_001076209.1

SMAD4 cDNA for Sus scrofa (Pig)

Code Product Name Vector Accession NO.
CSB-CL884388PI SMAD4 pUC NM_214072.1

SMAD4 cDNA for Rattus norvegicus (Rat)

Code Product Name Vector Accession NO.
CSB-CL021789RA Smad4 pUC NM_019275.2

SMAD4 ELISA Kit

SMAD4 ELISA Kit for Homo sapiens (Human)

Code Product Name Sample Types Sensitivity
CSB-E12749h Human Mothers against decapentaplegic homolog 4,Smad4 ELISA Kit serum, plasma, tissue homogenates, cell lysates 6.25 pg/mL

Newsletters

Get all the latest information on Events, Sales and Offers. Sign up for newsletter today.

Copyright © 2007-2018 www.cusabio.com CUSABIO TECHNOLOGY LLC All Rights Reserved.

Wait!

Join the 25,000 subscribers to get research hotpots, technical tips, latest information on events, sales and offers.

Sign up now!

We don't deal in spam.