Structural maintenance of chromosomes protein 1A is a protein in humans that is encoded by SMC1A gene. Involved in chromosome cohesion during cell cycle and in DNA repair. Central component of cohesin complex. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The cohesin complex may also play a role in spindle pole assembly during mitosis. Involved in DNA repair via its interaction with BRCA1 and its related phosphorylation by ATM, or via its phosphorylation by ATR. Works as a downstream effector both in the ATM/NBS1 branch and in the ATR/MSH2 branch of S-phase checkpoint.
The following SMC1A reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
SMC1A Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA614804ESR1HU | SMC1A Antibody |
Human | ELISA, IHC |
CSB-PA581416 | Phospho-SMC1A (Ser957) Antibody |
Human,Mouse | ELISA,WB,IHC |
CSB-PA775738 | SMC1A (Ab-957) Antibody |
Human,Mouse | ELISA,WB,IHC |
CSB-PA060229 | Phospho-SMC1A (S957) Antibody |
Human,Mouse | WB, IHC, ELISA |
CSB-PA060230 | Phospho-SMC1A (S966) Antibody |
Human,Mouse,Rat | WB, IHC, ELISA |
CSB-PA060231 | SMC1A Antibody |
Human,Mouse | WB, IHC, ELISA |
CSB-RA614804A957phHU | Phospho-SMC1A (S957) Recombinant Monoclonal Antibody |
Human | ELISA, WB |
CSB-RA149196A0HU | SMC1A Recombinant Monoclonal Antibody |
Human | ELISA, WB, IHC |
SMC1A Proteins for Bos taurus (Bovine)
Code | Product Name | Source |
---|---|---|
CSB-YP021812BO CSB-EP021812BO CSB-BP021812BO CSB-MP021812BO CSB-EP021812BO-B |
Recombinant Bovine Structural maintenance of chromosomes protein 1A (SMC1A), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
SMC1A Proteins for Xenopus laevis (African clawed frog)
Code | Product Name | Source |
---|---|---|
CSB-YP021812XBE CSB-EP021812XBE CSB-BP021812XBE CSB-MP021812XBE CSB-EP021812XBE-B |
Recombinant Xenopus laevis Structural maintenance of chromosomes protein 1A (smc1a), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
SMC1A Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP614804HU CSB-EP614804HU CSB-BP614804HU CSB-MP614804HU CSB-EP614804HU-B |
Recombinant Human Structural maintenance of chromosomes protein 1A (SMC1A), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
SMC1A Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
---|---|---|
CSB-YP863444MO CSB-EP863444MO CSB-BP863444MO CSB-MP863444MO CSB-EP863444MO-B |
Recombinant Mouse Structural maintenance of chromosomes protein 1A (Smc1a), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |