TRAC

TRAC, standing for T cell receptor alpha constant, encodes the constant region of the T cell receptor alpha chain. It is also commonly referred to as T cell antigen receptor alpha chain. This protein plays a crucial role in the immune response. It forms a heterodimer with the T cell receptor beta chain, enabling T cells to recognize antigens presented by major histocompatibility complex molecules. It is involved in the T cell receptor signaling pathway.
Dysregulation of TRAC can lead to various immune - related diseases, such as autoimmune disorders. In terms of drug development, efforts are being made to target the T cell receptor complex, including TRAC, for immunotherapy. Modulating the function of TRAC - containing receptors may hold promise for treating cancer and immune - related diseases.