TRADD Research Reagents

Tumor necrosis factor receptor type 1-associated DEATH domain protein is a protein in humans that is encoded by TRADD gene. The nuclear form acts as a tumor suppressor by preventing ubiquitination and degradation of isoform p19ARF/ARF of CDKN2A by TRIP12

The following TRADD reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

TRADD Antibody

TRADD Protein

TRADD Antibodies

TRADD Antibodies for Homo sapiens (Human)

Code	Product Name	Species Reactivity	Application
CSB-PA024145GA01HU	TRADD Antibody	Human,Mouse,Rat	ELISA,WB
CSB-PA621879ESR2HU	TRADD Antibody	Human	ELISA, WB, IHC
CSB-PA004322	TRADD Antibody	Human,Mouse,Monkey	WB, IHC, ELISA
CSB-PA621879EA01HU	TRADD Antibody	Human, Rat	ELISA, WB, IHC, IF, IP
CSB-PA621879EB01HU	TRADD Antibody, HRP conjugated	Human	ELISA
CSB-PA621879EC01HU	TRADD Antibody, FITC conjugated	Human
CSB-PA621879ED01HU	TRADD Antibody, Biotin conjugated	Human	ELISA

TRADD Antibodies for Danio rerio (Zebrafish) (Brachydanio rerio)

Code	Product Name	Species Reactivity	Application
CSB-PA867432XA01DIL	tradd Antibody	Danio rerio (Zebrafish) (Brachydanio rerio)	ELISA, WB (ensure identification of antigen)

TRADD Proteins

TRADD Proteins for Homo sapiens (Human)

Code	Product Name	Source
CSB-YP621879HU CSB-BP621879HU CSB-MP621879HU CSB-EP621879HU-B	Recombinant Human Tumor necrosis factor receptor type 1-associated DEATH domain protein(TRADD)	Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-EP621879HU	Recombinant Human Tumor necrosis factor receptor type 1-associated DEATH domain protein(TRADD)	E.coli

TRADD Proteins for Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)

Code	Product Name	Source
CSB-YP633137OEI CSB-EP633137OEI CSB-BP633137OEI CSB-MP633137OEI CSB-EP633137OEI-B	Recombinant Oncorhynchus mykiss Tumor necrosis factor receptor type 1-associated DEATH domain protein(tradd)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

TRADD Proteins for Bos taurus (Bovine)

Code	Product Name	Source
CSB-YP642522BO CSB-EP642522BO CSB-BP642522BO CSB-MP642522BO CSB-EP642522BO-B	Recombinant Bovine Tumor necrosis factor receptor type 1-associated DEATH domain protein(TRADD)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

TRADD Proteins for Xenopus laevis (African clawed frog)

Code	Product Name	Source
CSB-YP658365XBE CSB-EP658365XBE CSB-BP658365XBE CSB-MP658365XBE CSB-EP658365XBE-B	Recombinant Xenopus laevis Tumor necrosis factor receptor type 1-associated DEATH domain protein(tradd)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

TRADD Proteins for Mus musculus (Mouse)

Code	Product Name	Source
CSB-YP659708MO CSB-EP659708MO CSB-BP659708MO CSB-MP659708MO CSB-EP659708MO-B	Recombinant Mouse Tumor necrosis factor receptor type 1-associated DEATH domain protein(Tradd)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

TRADD Proteins for Danio rerio (Zebrafish) (Brachydanio rerio)

Code	Product Name	Source
CSB-YP867432DIL CSB-EP867432DIL CSB-BP867432DIL CSB-MP867432DIL CSB-EP867432DIL-B	Recombinant Danio rerio Tumor necrosis factor receptor type 1-associated DEATH domain protein(tradd)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

TRADD Background

Tumor necrosis factor receptor type 1-associated DEATH domain protein is a protein in humans that is encoded by the TRADD gene ^[1]. TRADD is a death domain-containing adaptor molecule that interacts with TNFRSF1A/TNFR1 and mediates programmed cell death signaling and NF-κB activation. This protein binds adaptor protein TRAF2, reduces the recruitment of inhibitor-of-apoptosis proteins (IAPs) by TRAF2, and thus suppresses TRAF2 mediated apoptosis.TRADD can also interact with receptor TNFRSF6/FAS and adaptor protein FADD/MORT1 and is involved in the Fas-induced cell death pathway. The nuclear form acts as a tumor suppressor by preventing ubiquitination and degradation of isoform p19ARF/ARF of CDKN2A by TRIP12.

[1] Hsu H, Xiong J, Goeddel DV (June 1995). The TNF receptor 1-associated protein TRADD signals cell death and NF-kappa B activation [J]. Cell. 81 (4): 495–504.

Popular Pathways

Apoptosis

Breast Cancer

Autophagy

Hippo Signaling Pathway

Wnt Signaling Pathway

Hippo signaling pathway

TGF-beta signaling pathway

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