WNT2

WNT2 (Wnt family member 2) is a secreted glycoprotein of the Wnt ligand family. It binds to Frizzled (Fz) receptors and LRP5/6 co-receptors, activating the canonical Wnt/β-catenin pathway—this regulates cell proliferation, differentiation, and tissue morphogenesis during development and adult homeostasis.
Aberrant WNT2 overexpression links to lung adenocarcinoma and colorectal cancer, driving tumor growth and metastasis. Drug development targets Wnt signaling components: Porcupine inhibitors (blocking Wnt secretion) are in clinical trials for WNT2-dysregulated cancers, while direct WNT2-targeted agents remain in preclinical stages.

Validated Data

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

WNT2 Antibody (CSB-PA026133ESR1HU)

Validated Data

Western blot
All lanes: Protein Wnt-2 antibody at 2μg/ml
Lane 1: HepG2 whole cell lysate
Lane 2: MCF-7 whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 40 kDa
Observed band size: 40 kDa

Immunohistochemistry of paraffin-embedded human colon tissue using CSB-PA026133ESR1HU at dilution of 1:100

Immunohistochemistry of paraffin-embedded human lung tissue using CSB-PA026133ESR1HU at dilution of 1:100

Immunohistochemistry of paraffin-embedded human placenta tissue using CSB-PA026133ESR1HU at dilution of 1:100

Human Protein Wnt-2(WNT2) ELISA kit (CSB-EL026133HU)

Validated Data

Code: CSB-EL026133HU

Size: 96T,5×96T,10×96T

Sensitivity: 0.11 ng/mL

Detection Range: 0.45 ng/mL-30 ng/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

The following WNT2 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

WNT2 Antibodies

WNT2 Proteins

WNT2 ELISA Kits

WNT2 Antibodies

WNT2 Antibodies for Homo sapiens (Human)

Code	Product Name	Species Reactivity	Application
CSB-PA026133GA01HU	WNT2 Antibody	Human,Mouse,Rat	ELISA,WB,IHC
CSB-PA026133ESR1HU	WNT2 Antibody	Human	ELISA, WB, IHC
CSB-PA782193	WNT2 Antibody	Human,Mouse	ELISA,WB,IHC

WNT2 Antibodies for Drosophila melanogaster (Fruit fly)

Code	Product Name	Species Reactivity	Application
CSB-PA026133XA01DLU	Wnt2 Antibody	Drosophila melanogaster (Fruit fly)	ELISA, WB (ensure identification of antigen)

WNT2 Antibodies for Danio rerio (Zebrafish) (Brachydanio rerio)

Code	Product Name	Species Reactivity	Application
CSB-PA838723XA01DIL	wnt2 Antibody	Danio rerio (Zebrafish) (Brachydanio rerio)	ELISA, WB (ensure identification of antigen)

WNT2 Antibodies for Mus musculus (Mouse)

Code	Product Name	Species Reactivity	Application
CSB-PA026133ZA01MO	Wnt2 Antibody	Mus musculus	ELISA, WB (ensure identification of antigen)

WNT2 Proteins

WNT2 Proteins for Mus musculus (Mouse)

Code	Product Name	Source
CSB-YP026133MO CSB-BP026133MO CSB-EP026133MO-B	Recombinant Mouse Protein Wnt-2 (Wnt2)	Yeast Baculovirus In Vivo Biotinylation in E.coli
CSB-EP026133MO	Recombinant Mouse Protein Wnt-2 (Wnt2)	E.coli

WNT2 Proteins for Homo sapiens (Human)

Code	Product Name	Source
CSB-YP026133HU	Recombinant Human Protein Wnt-2 (WNT2)	Yeast
CSB-EP026133HU	Recombinant Human Protein Wnt-2 (WNT2)	E.coli
CSB-MP026133HU CSB-EP026133HU-B	Recombinant Human Protein Wnt-2 (WNT2)	Mammalian cell In Vivo Biotinylation in E.coli
CSB-BP026133HU	Recombinant Human Protein Wnt-2 (WNT2)	Baculovirus

WNT2 Proteins for Felis catus (Cat) (Felis silvestris catus)

Code	Product Name	Source
CSB-YP026133CA CSB-EP026133CA CSB-BP026133CA CSB-MP026133CA CSB-EP026133CA-B	Recombinant Cat Protein Wnt-2 (WNT2)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

WNT2 Proteins for Bos taurus (Bovine)

Code	Product Name	Source
CSB-YP026133BO CSB-EP026133BO CSB-BP026133BO CSB-MP026133BO CSB-EP026133BO-B	Recombinant Bovine Protein Wnt-2 (WNT2)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

WNT2 Proteins for Drosophila melanogaster (Fruit fly)

Code	Product Name	Source
CSB-YP026133DLU CSB-EP026133DLU CSB-BP026133DLU CSB-MP026133DLU CSB-EP026133DLU-B	Recombinant Drosophila melanogaster Protein Wnt-2 (Wnt2)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

WNT2 Proteins for Papio anubis (Olive baboon)

Code	Product Name	Source
CSB-YP026133ERI CSB-EP026133ERI CSB-BP026133ERI CSB-MP026133ERI CSB-EP026133ERI-B	Recombinant Papio anubis Protein Wnt-2 (WNT2)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

WNT2 Proteins for Echinops telfairi (Lesser hedgehog tenrec)

Code	Product Name	Source
CSB-YP026133EJK CSB-EP026133EJK CSB-BP026133EJK CSB-MP026133EJK CSB-EP026133EJK-B	Recombinant Echinops telfairi Protein Wnt-2 (WNT2)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

WNT2 Proteins for Muntiacus muntjak (Barking deer) (Indian muntjac)

Code	Product Name	Source
CSB-YP600342MJP CSB-EP600342MJP CSB-BP600342MJP CSB-MP600342MJP CSB-EP600342MJP-B	Recombinant Muntiacus muntjak Protein Wnt-2 (WNT2)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

WNT2 Proteins for Loxodonta africana (African elephant)

Code	Product Name	Source
CSB-YP606036LJC CSB-EP606036LJC CSB-BP606036LJC CSB-MP606036LJC CSB-EP606036LJC-B	Recombinant Loxodonta africana Protein Wnt-2 (WNT2)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

WNT2 Proteins for Rhinolophus ferrumequinum (Greater horseshoe bat)

Code	Product Name	Source
CSB-YP639483RKD CSB-EP639483RKD CSB-BP639483RKD CSB-MP639483RKD CSB-EP639483RKD-B	Recombinant Rhinolophus ferrumequinum Protein Wnt-2 (WNT2)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

WNT2 Proteins for Eulemur macaco macaco (Black lemur)

Code	Product Name	Source
CSB-YP640411EPG CSB-EP640411EPG CSB-BP640411EPG CSB-MP640411EPG CSB-EP640411EPG-B	Recombinant Eulemur macaco macaco Protein Wnt-2 (WNT2)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

WNT2 Proteins for Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)

Code	Product Name	Source
CSB-YP642258PYX CSB-EP642258PYX CSB-BP642258PYX CSB-MP642258PYX CSB-EP642258PYX-B	Recombinant Pongo abelii Protein Wnt-2 (WNT2)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

WNT2 Proteins for Chlorocebus aethiops (Green monkey) (Cercopithecus aethiops)

Code	Product Name	Source
CSB-YP644159DSU CSB-EP644159DSU CSB-BP644159DSU CSB-MP644159DSU CSB-EP644159DSU-B	Recombinant Chlorocebus aethiops Protein Wnt-2 (WNT2)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

WNT2 Proteins for Gorilla gorilla gorilla (Western lowland gorilla)

Code	Product Name	Source
CSB-YP646268GGZ CSB-EP646268GGZ CSB-BP646268GGZ CSB-MP646268GGZ CSB-EP646268GGZ-B	Recombinant Gorilla gorilla gorilla Protein Wnt-2 (WNT2)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

WNT2 Proteins for Callithrix jacchus (White-tufted-ear marmoset)

Code	Product Name	Source
CSB-YP646917CYL CSB-EP646917CYL CSB-BP646917CYL CSB-MP646917CYL CSB-EP646917CYL-B	Recombinant Callithrix jacchus Protein Wnt-2 (WNT2)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

WNT2 Proteins for Carollia perspicillata (Seba's short-tailed bat)

Code	Product Name	Source
CSB-YP648499CCAH CSB-EP648499CCAH CSB-BP648499CCAH CSB-MP648499CCAH CSB-EP648499CCAH-B	Recombinant Carollia perspicillata Protein Wnt-2 (WNT2)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

WNT2 Proteins for Pan troglodytes (Chimpanzee)

Code	Product Name	Source
CSB-YP648500EQV CSB-EP648500EQV CSB-BP648500EQV CSB-MP648500EQV CSB-EP648500EQV-B	Recombinant Pan troglodytes Protein Wnt-2 (WNT2)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

WNT2 Proteins for Otolemur garnettii (Small-eared galago) (Garnett's greater bushbaby)

Code	Product Name	Source
CSB-YP648503OFS CSB-EP648503OFS CSB-BP648503OFS CSB-MP648503OFS CSB-EP648503OFS-B	Recombinant Otolemur garnettii Protein Wnt-2 (WNT2)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

WNT2 Proteins for Equus caballus (Horse)

Code	Product Name	Source
CSB-YP649285HO CSB-EP649285HO CSB-BP649285HO CSB-MP649285HO CSB-EP649285HO-B	Recombinant Horse Protein Wnt-2 (WNT2)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

WNT2 Proteins for Didelphis virginiana (North American opossum) (Didelphis marsupialis virginiana)

Code	Product Name	Source
CSB-YP650844DKL CSB-EP650844DKL CSB-BP650844DKL CSB-MP650844DKL CSB-EP650844DKL-B	Recombinant Didelphis marsupialis virginiana Protein Wnt-2 (WNT2)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

WNT2 Proteins for Monodelphis domestica (Gray short-tailed opossum)

Code	Product Name	Source
CSB-YP651629MUE CSB-EP651629MUE CSB-BP651629MUE CSB-MP651629MUE CSB-EP651629MUE-B	Recombinant Monodelphis domestica Protein Wnt-2 (WNT2)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

WNT2 Proteins for Plecturocebus moloch (Dusky titi monkey) (Callicebus moloch)

Code	Product Name	Source
CSB-YP651631CYE CSB-EP651631CYE CSB-BP651631CYE CSB-MP651631CYE CSB-EP651631CYE-B	Recombinant Callicebus moloch Protein Wnt-2 (WNT2)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

WNT2 Proteins for Microcebus murinus (Lesser mouse lemur) (Gray Mouse Lemur)

Code	Product Name	Source
CSB-YP652409MFU CSB-EP652409MFU CSB-BP652409MFU CSB-MP652409MFU CSB-EP652409MFU-B	Recombinant Microcebus murinus Protein Wnt-2 (WNT2)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

WNT2 Proteins for Danio rerio (Zebrafish) (Brachydanio rerio)

Code	Product Name	Source
CSB-YP838723DIL CSB-EP838723DIL CSB-BP838723DIL CSB-MP838723DIL CSB-EP838723DIL-B	Recombinant Danio rerio Protein Wnt-2 (wnt2)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

WNT2 ELISA Kit

WNT2 ELISA Kit for Homo sapiens (Human)

Code	Product Name	Sample Types	Sensitivity
CSB-EL026133HU	Human Protein Wnt-2(WNT2) ELISA kit	serum, plasma, tissue homogenates	0.11 ng/mL

WNT2 ELISA Kit for Mus musculus (Mouse)

Code	Product Name	Sample Types	Sensitivity
CSB-EL026133MO	Mouse Protein Wnt-2(WNT2) ELISA kit	serum, plasma, tissue homogenates	3.9 pg/mL

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WNT2

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