Recombinant Macaca mulatta Interleukin-10(IL10)

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Code CSB-EP011580MOW
Product Type Recombinant Protein
Size US$2466Purchase it in Cusabio online store
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Uniprot No. P51496
Lead Time 3-7 business days
Relevance Inhibits the synthesis of a number of cytokines, including IFN-gamma, IL-2, IL-3, TNF and GM-CSF produced by activated macrophages and by helper T-cells.
Image
  • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

Storage Buffer Tris-based buffer,50% glycerol
Alias Cytokine synthesis inhibitory factor
Species Macaca mulatta (Rhesus macaque)
Purity Greater than 90% as determined by SDS-PAGE.
Sequence SPGQGTQSENSCTRFPGNLPHMLRDLRDAFSRVKTFFQMKDQLDNILLKESLLEDFKGYLGCQALSEMIQFYLEEVMPQAENHDPDIKEHVNSLGENLKTLRLRLRRCHRFLPCENKSKAVEQVKNAFSKLQEKGVYKAMSEFDIFINYIEAYMTMKIQN
Research Area Immunology
Source E.coli
Gene Names IL10
Protein Names Recommended name: Interleukin-10 Short name= IL-10 Alternative name(s): Cytokine synthesis inhibitory factor Short name= CSIF
Expression Region 19-178aa
Tag Info N-terminal 6xHis-B2M-tagged
Mol. Weight 32.7kDa
Protein Description Full Length of Mature Protein
Storage The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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Function Inhibits the synthesis of a number of cytokines, including IFN-gamma, IL-2, IL-3, TNF and GM-CSF produced by activated macrophages and by helper T-cells.
Subcellular Location Secreted
Protein Families IL-10 family
Database Links

KEGG: mcc:694931

STRING: 9544.ENSMMUP00000031022

UniGene: Mmu.3374

Pathway Jak-STAT signaling pathway
T cell receptor signaling pathway
FoxO signaling pathway

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