CADM1 (Cell Adhesion Molecule 1), also known as SynCAM1 (Synaptic Cell Adhesion Molecule 1), participates in various biological processes and the development of diseases.The extracellular domain of ADM1 consists of an N-terminal signal sequence, three Ig-like domains, and a C-terminal domain. The first Ig-like domain is involved in cell adhesion and signal transduction. The intracellular domain of CADM1 includes a short cytoplasmic region and a long cytoplasmic region. The former contains a peptide cleavage site and several phosphorylation sites, while the latter contains multiple protein interaction sites and signal regulatory domains. CADM1 is expressed in neurons, immune cells, tumors, and other cell types. It influences cell adhesion, migration, proliferation, apoptosis, and other biological behaviors through its extracellular domain and intracellular signaling pathways.
Read more: CADM1: an Immunoglobulin Superfamily Molecule, a New Tumor Suppressor Gene!
Recombinant Mouse Cell adhesion molecule 1(Cadm1),partial (Active) CSB-MP004425MO
Validated Data
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Activity: Measured by its binding ability in a functional ELISA. Immobilized Mouse CADM1 at 2μg/mL can bind Mouse CRTAM (CSB-MP614820MO), the EC50 is 52.61-92.92 ng/mL.
The following CADM1 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
CADM1 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA004425GA01HU | CADM1 Antibody |
Human,Mouse,Rat | ELISA,WB |
CSB-PA004425ESR2HU | CADM1 Antibody |
Human | ELISA, IHC |
CSB-PA112392 | CADM1 Antibody |
Human,Mouse | ELISA,WB |
CSB-PA004340 | CADM1 Antibody |
Human,Mouse | WB, IF, ELISA |
CADM1 Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
---|---|---|
CSB-YP004425MO CSB-EP004425MO CSB-BP004425MO CSB-MP004425MO CSB-EP004425MO-B |
Recombinant Mouse Cell adhesion molecule 1 (Cadm1), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-MP004425MO | Recombinant Mouse Cell adhesion molecule 1 (Cadm1), partial (Active) |
Mammalian cell |
CADM1 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP004425HU CSB-EP004425HU CSB-BP004425HU CSB-MP004425HU CSB-EP004425HU-B |
Recombinant Human Cell adhesion molecule 1 (CADM1), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |