CCR9 possesses seven transmembrane domains, two cytoplasmic regions, and one extracellular domain, enabling it to bind its specific ligand and transduce signals. Its ligand is CCL25, also known as TECK, a chemokine produced by intestinal epithelial cells that attracts CCR9-expressing immune cells, such as T lymphocytes and macrophages, to migrate towards the intestine. The CCR9/CCL25 signaling pathway plays a crucial role in intestinal immune regulation, particularly in the pathogenesis of inflammatory bowel diseases like Crohn's disease and ulcerative colitis.
Recombinant Human C-C chemokine receptor type 9 (CCR9)-VLPs (Active)
Validated Data
The purity of VLPs was greater than 95% as determined by HPLC-SEC.
CSB-MP004848HU is detected by Mouse anti-6*His monoclonal antibody.
Activity: Measured by its binding ability in a functional ELISA. Immobilized Human CCR9 at 10μg/mL can bind Anti-CCR9 recombinant antibody (CSB-RA004848MA1HU),the EC50 is 31.67-36.83 ng/mL.The VLPs (CSB-MP3838) is negative control.
The following CCR9 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
CCR9 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA035070 | CCR9 Antibody |
Human,Mouse | ELISA,IHC |
CSB-PA293047 | CCR9 Antibody |
Human,Mouse | ELISA,IHC |
CSB-RA004848A0HU | CCR9 Recombinant Monoclonal Antibody |
Human, Mouse | ELISA, WB, IF, IP |
CSB-RA004848MA1HU | CCR9 Recombinant Monoclonal Antibody |
Human | ELISA |
CCR9 Proteins for Ovis aries (Sheep)
Code | Product Name | Source |
---|---|---|
CSB-CF631240SH | Recombinant Sheep C-C chemokine receptor type 9 (CCR9) |
in vitro E.coli expression system |
CSB-YP631240SH1 CSB-EP631240SH1 CSB-BP631240SH1 CSB-MP631240SH1 CSB-EP631240SH1-B |
Recombinant Sheep C-C chemokine receptor type 9 (CCR9), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CCR9 Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
---|---|---|
CSB-CF894369MO | Recombinant Mouse C-C chemokine receptor type 9 (Ccr9) |
in vitro E.coli expression system |
CSB-YP894369MO1 CSB-EP894369MO1 CSB-BP894369MO1 CSB-MP894369MO1 CSB-EP894369MO1-B |
Recombinant Mouse C-C chemokine receptor type 9 (Ccr9), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CCR9 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-CF004848HU | Recombinant Human C-C chemokine receptor type 9 (CCR9) |
in vitro E.coli expression system |
CSB-YP004848HU1 CSB-BP004848HU1 CSB-MP004848HU1 CSB-EP004848HU1-B |
Recombinant Human C-C chemokine receptor type 9 (CCR9), partial |
Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-EP004848HU1 | Recombinant Human C-C chemokine receptor type 9 (CCR9), partial |
E.coli |
CSB-MP004848HU | Recombinant Human C-C chemokine receptor type 9 (CCR9)-VLPs (Active) |
Mammalian cell |