CLEC9A Research Reagents

C-type lectin 9 family A member (CLEC9A), also known as dendritic cell-NK cell lectin cluster receptor 1 (DNCR1), is a dendritic cell surface molecule discovered in 2008, belonging to non-classical type II Transmembrane C-type lectin-like receptor (CLR). The CLEC9A molecule consists of three parts: N-terminal cytoplasmic domain, transmembrane domain and C-terminal extracellular domain. The extracellular domain includes neck region and a C-type lectin-like domain. The expression of CLEC9A molecule is highly DC-restricted. Mouse CLEC9A is mainly expressed on the surface of CD8α+DC and CD103+CD11b- ordinary dendritic cells. In human peripheral blood, CLEC9A is mainly expressed on blood dendritic cell antigen 3 (BDC4A3). Positive myeloid dendritic cells (mDC), namely BDCA3+mDC surface. Human BDCA3+CLEC9A+DC as an independent DC subset, equivalent to mouse CD8α+DC, can mediate endocytosis, cross-present antigens to CD8+ T cells, and stimulate cytotoxic T lymphocyte (CTL) responses in vivo.

The following CLEC9A reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

CLEC9A Antibodies

CLEC9A Antibodies for Homo sapiens (Human)

CLEC9A Proteins

CLEC9A Proteins for Homo sapiens (Human)

CLEC9A Proteins for Mus musculus (Mouse)

CLEC9A Proteins for Rattus norvegicus (Rat)

CLEC9A ELISA Kit

CLEC9A ELISA Kit for Homo sapiens (Human)

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