DLK1, also known as Delta-like 1 homolog, is a transmembrane protein with common aliases including pG2 and FA1. It functions by interacting with Notch receptors, influencing cell fate determination and differentiation. DLK1 is involved in the Notch signaling pathway, which is crucial for normal development and tissue homeostasis.
Alterations in DLK1 have been associated with various diseases such as obesity, diabetes, and certain cancers. Regarding drug development, research is ongoing to target DLK1 and its related pathways. Some strategies aim to modulate its activity to treat the associated conditions, yet significant progress is still awaited.
Recombinant Human Protein delta homolog 1 (DLK1), partial (Active) (CSB-MP006945HUd7)
Validated Data
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Activity
Measured by its binding ability in a functional ELISA. Immobilized Human DLK1 at 2 μg/ml can bind Anti-DLK1 recombinant antibody (CSB-RA006945MA1HU). The EC50 is 1.598-1.804 ng/mL.
Activity
Measured by its binding ability in a functional ELISA. Immobilized Human DLK1 at 2 μg/ml can bind Anti-DLK1 recombinant antibody (CSB-RA006945MA2HU). The EC50 is 1.935-2.143 ng/mL.
The purity of DLK1 was greater than 95% as determined by SEC-HPLC
Recombinant Human Protein delta homolog 1 (DLK1), partial (CSB-EP006945HU)
Validated Data
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
DLK1 Recombinant Monoclonal Antibody (CSB-RA006945MA1HU)
Validated Data
The Binding Activity of Human DLK1 with Anti-DLK1 recombinant antibody
Activity: Measured by its binding ability in a functional ELISA. Immobilized Human DLK1 protein (CSB-MP006945HUd7) at 2 μg/mL can bind Anti-DLK1 recombinant antibody. The EC50 is 1.598-1.804 ng/mL.
The following DLK1 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
DLK1 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA006945GA01HU | DLK1 Antibody | Human,Mouse,Rat | ELISA,WB |
CSB-PA006945LA01HU | DLK1 Antibody | Human, Rat | ELISA, WB, IHC, IF |
CSB-PA824488 | DLK1 Antibody | Human | ELISA,WB |
CSB-PA120648 | DLK1 Antibody | Human,Mouse | ELISA,WB |
CSB-RA006945MA1HU | DLK1 Recombinant Monoclonal Antibody | Human | ELISA |
CSB-RA006945MA2HU | DLK1 Recombinant Monoclonal Antibody | Human | ELISA |
DLK1 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP006945HU | Recombinant Human Protein delta homolog 1 (DLK1), partial | Yeast |
CSB-EP006945HU | Recombinant Human Protein delta homolog 1 (DLK1), partial | E.coli |
CSB-BP006945HU CSB-EP006945HU-B |
Recombinant Human Protein delta homolog 1 (DLK1), partial | Baculovirus In Vivo Biotinylation in E.coli |
CSB-MP006945HU | Recombinant Human Protein delta homolog 1 (DLK1), partial | Mammalian cell |
CSB-MP006945HUd7 | Recombinant Human Protein delta homolog 1 (DLK1), partial (Active) | Mammalian cell |
DLK1 ELISA Kit for Mus musculus (Mouse)
Code | Product Name | Sample Types | Sensitivity |
---|---|---|---|
CSB-EL006945MO | Mouse Protein delta homolog 1(DLK1) ELISA kit | serum, plasma, tissue homogenates | 3.9 pg/mL |