DNASE1L3

DNASE1L3 is a type of nuclease enzyme with the ability to degrade DNA. Its active site can specifically recognize DNA strands and cleave them, breaking them down into smaller fragments. DNASE1L3 plays a role in maintaining nucleic acid stability within cells. It can degrade residual cellular DNA, preventing self-immune reactions and inflammation. Moreover, DNASE1L3 also plays a significant role in the process of cellular apoptosis, aiding in the clearance of DNA released by apoptotic cells.

Aberrant activity or defects in DNASE1L3 may lead to the occurrence of autoimmune reactions, associated with the pathogenesis of certain autoimmune diseases such as systemic lupus erythematosus. Understanding its mechanisms can provide new insights into the treatment of inflammatory diseases and conditions related to cellular apoptosis.

Validated Data

SDS-PAGE

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

LC-MS/MS

Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-EP621686HU could indicate that this peptide derived from E.coli-expressed Homo sapiens (Human) DNASE1L3.

LC-MS/MS

The following DNASE1L3 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

DNASE1L3 Antibodies

DNASE1L3 Proteins

DNASE1L3 ELISA Kits

DNASE1L3 Antibodies

DNASE1L3 Antibodies for Homo sapiens (Human)

Code	Product Name	Species Reactivity	Application
CSB-PA007052GA01HU	DNASE1L3 Antibody	Human,Mouse,Rat	ELISA,WB
CSB-PA115883	DNASE1L3 Antibody	Human,Mouse,Rat	ELISA,WB
CSB-PA621686EA01HU	DNASE1L3 Antibody	Human	ELISA, IHC
CSB-PA621686EB01HU	DNASE1L3 Antibody, HRP conjugated	Human	ELISA
CSB-PA621686EC01HU	DNASE1L3 Antibody, FITC conjugated	Human
CSB-PA621686ED01HU	DNASE1L3 Antibody, Biotin conjugated	Human	ELISA

DNASE1L3 Proteins

DNASE1L3 Proteins for Mus musculus (Mouse)

Code	Product Name	Source
CSB-YP007052MO CSB-BP007052MO CSB-MP007052MO CSB-EP007052MO-B	Recombinant Mouse Deoxyribonuclease gamma (Dnase1l3)	Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-EP007052MO	Recombinant Mouse Deoxyribonuclease gamma (Dnase1l3)	E.coli
CSB-EP007052MOb0	Recombinant Mouse Deoxyribonuclease gamma (Dnase1l3)	E.coli

DNASE1L3 Proteins for Rattus norvegicus (Rat)

Code	Product Name	Source
CSB-YP007052RA CSB-EP007052RA CSB-BP007052RA CSB-MP007052RA CSB-EP007052RA-B	Recombinant Rat Deoxyribonuclease gamma (Dnase1l3)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

DNASE1L3 Proteins for Homo sapiens (Human)

Code	Product Name	Source
CSB-YP621686HU CSB-MP621686HU CSB-EP621686HU-B	Recombinant Human Deoxyribonuclease gamma (DNASE1L3)	Yeast Mammalian cell In Vivo Biotinylation in E.coli
CSB-EP621686HU	Recombinant Human Deoxyribonuclease gamma (DNASE1L3)	E.coli
CSB-EP621686HUe1	Recombinant Human Deoxyribonuclease gamma (DNASE1L3)	E.coli
CSB-BP621686HU	Recombinant Human Deoxyribonuclease gamma (DNASE1L3)	Baculovirus
CSB-BP621686HUb1	Recombinant Human Deoxyribonuclease gamma (DNASE1L3)	Baculovirus
CSB-EP621686HUb1	Recombinant Human Deoxyribonuclease gamma (DNASE1L3)	E.coli
CSB-EP621686HUc7	Recombinant Human Deoxyribonuclease gamma (DNASE1L3)	E.coli
CSB-EP621686HUd7	Recombinant Human Deoxyribonuclease gamma (DNASE1L3)	E.coli
CSB-EP621686HUg5	Recombinant Human Deoxyribonuclease gamma (DNASE1L3)	E.coli

DNASE1L3 ELISA Kit

DNASE1L3 ELISA Kit for Homo sapiens (Human)

Code	Product Name	Sample Types	Sensitivity
CSB-EL007052HU	Human Deoxyribonuclease gamma(DNASE1L3) ELISA kit	serum, plasma, tissue homogenates, cell lysates	5.86 pg/mL

Promotions

CUSABIO Premium Active Proteins 20% OFF SALE

Popular Pathways

Apoptosis

Breast Cancer

Autophagy

Hippo Signaling Pathway

Wnt Signaling Pathway

Hippo signaling pathway

TGF-beta signaling pathway

Apoptosis mediated by mitochondria The Overview of Hippo Signaling Pathway The Overview of Autophagy Crosstalk Between Autophagy and Apoptosis The Overview of Wnt Signaling Pathway The Overview of Breast Cancer: Related Signaling Pathways, Therapeutic Targets The overview of TGF-β signaling pathway PI3K-Akt Signaling Pathway and Cancer Apoptosis mediated by endoplasmic reticulum Apoptosisi mediated by death receptor Aesthetic Appreciation of Apoptosis Signal Pathway An Overview of Cell Death: Necrosis and Apoptosis Do You Really Know TGF-β Superfamily? Double-Edged Sword: TGF-β The Overview of PI3-Alt Signaling Pathway How to Inquire and Utilize the Signal Pathway on KEGG LPS/TLR4 Signal Transduction Pathway Epigenetic Histone Modifications Pathway What A Paradoxical TNF Signaling Pathway-Based on Different Receptors The Overview of Fc Receptors- Classification, Related Signaling Pathways and Application

DNASE1L3

Popular Product: