FLT1

Vascular endothelial growth factor receptor 1 is a protein in humans that is encoded by FLT1 gene. Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFB and PGF, and plays an essential role in the development of embryonic vasculature, the regulation of angiogenesis, cell survival, cell migration, macrophage function, chemotaxis, and cancer cell invasion. May play an essential role as a negative regulator of embryonic angiogenesis by inhibiting excessive proliferation of endothelial cells. Can promote endothelial cell proliferation, survival and angiogenesis in adulthood. Its function in promoting cell proliferation seems to be cell-type specific. Promotes PGF-mediated proliferation of endothelial cells, proliferation of some types of cancer cells, but does not promote proliferation of normal fibroblasts (in vitro). Has very high affinity for VEGFA and relatively low protein kinase activity.

FLT1 Antibodies

FLT1 Antibodies for Homo sapiens (Human)

FLT1 Proteins

FLT1 Proteins for Homo sapiens (Human)

FLT1 Proteins for Mus musculus (Mouse)

FLT1 Proteins for Rattus norvegicus (Rat)

FLT1 Proteins for Gallus gallus (Chicken)

FLT1 ELISA Kit

FLT1 ELISA Kit for Mus musculus (Mouse)

FLT1 ELISA Kit for Rattus norvegicus (Rat)

FLT1 ELISA Kit for Homo sapiens (Human)

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