FOXO1

Forkhead box protein O1 is a protein in humans that is encoded by FOXO1 gene. Transcription factor that is the main target of insulin signaling and regulates metabolic homeostasis in response to oxidative stress. Binds to the insulin response element (IRE) with consensus sequence 5'-TT[G/A]TTTTG-3' and the related Daf-16 family binding element (DBE) with consensus sequence 5'-TT[G/A]TTTAC-3'. Activity suppressed by insulin. Main regulator of redox balance and osteoblast numbers and controls bone mass. Orchestrates the endocrine function of the skeleton in regulating glucose metabolism. Acts synergistically with ATF4 to suppress osteocalcin/BGLAP activity, increasing glucose levels and triggering glucose intolerance and insulin insensitivity.

FOXO1 Antibodies

FOXO1 Antibodies for Homo sapiens (Human)

FOXO1 Antibodies for Human

FOXO1 Proteins

FOXO1 Proteins for Homo sapiens (Human)

FOXO1 Proteins for Xenopus laevis (African clawed frog)

FOXO1 Proteins for Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)

FOXO1 Proteins for Ictidomys tridecemlineatus (Thirteen-lined ground squirrel) (Spermophilus tridecemlineatus)

FOXO1 Proteins for Mus musculus (Mouse)

FOXO1 ELISA Kit

FOXO1 ELISA Kit for Homo sapiens (Human)

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