HLA-E (Human Leukocyte Antigen E) is a major histocompatibility complex class I (MHC-I) molecule. MHC molecules play a crucial role in the immune system by aiding in the recognition and differentiation between self-cells and foreign cells. HLA-E consists of an α chain and a β2 microglobulin chain. Its structure allows it to present peptide segments on the cell surface, displaying antigens from within the cell. The primary role of HLA-E in the immune system involves binding to T-cell receptors and regulating self-recognition and immune responses. Typically, HLA-E binds to peptides produced within the cell and presents them on the cell surface, aiding the immune system in identifying healthy self-cells. As a subtype of MHC-I molecules, HLA-E plays a significant role in the immune system, potentially being linked to the development of certain diseases such as autoimmune conditions and specific infections. Research into its function and regulatory mechanisms not only aids in a deeper understanding of the immune system and immune-related disorders but also offers new insights for disease treatments and immune vaccine design.
Recombinant Human HLA class I histocompatibility antigen, alpha chain E (HLA-E),partial
Validated Data
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
The following HLA-E reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
HLA-E Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA320269LA01HU | HLA-E Antibody | Human | ELISA |
CSB-PA320269LB01HU | HLA-E Antibody, HRP conjugated | Human | ELISA |
CSB-PA320269LC01HU | HLA-E Antibody, FITC conjugated | Human | |
CSB-PA320269LD01HU | HLA-E Antibody, Biotin conjugated | Human | ELISA |
HLA-E Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-EP320269HU | Recombinant Human HLA class I histocompatibility antigen, alpha chain E (HLA-E), partial | E.coli |
CSB-YP320269HU CSB-BP320269HU CSB-MP320269HU CSB-EP320269HU-B |
Recombinant Human HLA class I histocompatibility antigen, alpha chain E (HLA-E), partial | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-BP320269HU | Recombinant Human HLA class I histocompatibility antigen, alpha chain E (HLA-E), partial | Baculovirus |
HLA-E ELISA Kit for Homo sapiens (Human)
Code | Product Name | Sample Types | Sensitivity |
---|---|---|---|
CSB-EL010507HU | Human major histocompatibility complex, class I, E (HLA-E) ELISA kit | serum, plasma, cell culture supernates, tissue homogenates | 7.81 pg/mL |