IGFL1

It is a member of the insulin-like growth factor signaling molecule family and belongs to the IGF-like (IGFL) family. The IGFL gene encodes a protein of approximately 100 amino acids, including 11 conserved cysteine residues at fixed positions, including two CC motifs. In humans, the IGFL family comprises four genes (IGFL1, IGFL2, IGFL3, and IGFL4) and two pseudogenes (IGFL1P1 and IGFL1P2). Existing data indicate that IGFL1 is not expressed in a wide range of tissues, including the adrenal gland, bone marrow, brain, prostate, skin, small intestine, thyroid, and uterus. However, it is expressed in fetal skin, normal breast tissue, ovaries, and the spinal cord. Additionally, some databases show expression of IGFL1 in cancer cells, including squamous cell carcinoma, uterine tumors, and head and neck tumors, suggesting that IGFL1 may emerge as a potential novel cancer target.

More Interesting read related IGFL1: A Novel Secretory Protein of IGF-Like Family Presents a High Cancer-Promoting Potential!

Popular Product

Recombinant Human Insulin growth factor-like family member 1(IGFL1) (Active) CSB-MP764932HU

Validated Data

SDS

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

ELISA

Activity: Measured by its binding ability in a functional ELISA. Immobilized Human IGFLR1 (CSB-MP862025HU) at 2 μg/ml can bind Human IGFL1, the EC₅₀ is 32.33-47.52 ng/mL.