It is a member of the insulin-like growth factor signaling molecule family and belongs to the IGF-like (IGFL) family. The IGFL gene encodes a protein of approximately 100 amino acids, including 11 conserved cysteine residues at fixed positions, including two CC motifs. In humans, the IGFL family comprises four genes (IGFL1, IGFL2, IGFL3, and IGFL4) and two pseudogenes (IGFL1P1 and IGFL1P2). Existing data indicate that IGFL1 is not expressed in a wide range of tissues, including the adrenal gland, bone marrow, brain, prostate, skin, small intestine, thyroid, and uterus. However, it is expressed in fetal skin, normal breast tissue, ovaries, and the spinal cord. Additionally, some databases show expression of IGFL1 in cancer cells, including squamous cell carcinoma, uterine tumors, and head and neck tumors, suggesting that IGFL1 may emerge as a potential novel cancer target.
Recombinant Human Insulin growth factor-like family member 1(IGFL1) (Active) CSB-MP764932HU
Validated Data
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Activity: Measured by its binding ability in a functional ELISA. Immobilized Human IGFLR1 (CSB-MP862025HU) at 2 μg/ml can bind Human IGFL1, the EC50 is 32.33-47.52 ng/mL.
The following IGFL1 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
IGFL1 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA764932ZA01HU | IGFL1 Antibody |
Homo sapiens | ELISA, WB (ensure identification of antigen) |
IGFL1 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP764932HU CSB-EP764932HU CSB-BP764932HU CSB-MP764932HU CSB-EP764932HU-B |
Recombinant Human Insulin growth factor-like family member 1 (IGFL1) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-EP764932HU | Recombinant Human Insulin growth factor-like family member 1 (IGFL1) |
E.coli |
CSB-MP764932HU | Recombinant Human Insulin growth factor-like family member 1 (IGFL1) (Active) |
Mammalian cell |
CSB-MP764932HUh8 | Recombinant Human Insulin growth factor-like family member 1 (IGFL1) |
Mammalian cell |