KDR

Vascular endothelial growth factor receptor 2 is a protein in humans that is encoded by KDR gene. Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFC and VEGFD. Plays an essential role in the regulation of angiogenesis, vascular development, vascular permeability, and embryonic hematopoiesis. Promotes proliferation, survival, migration and differentiation of endothelial cells. Promotes reorganization of the actin cytoskeleton. Isoforms lacking a transmembrane domain, such as isoform 2 and isoform 3, may function as decoy receptors for VEGFA, VEGFC and/or VEGFD. Isoform 2 plays an important role as negative regulator of VEGFA- and VEGFC-mediated lymphangiogenesis by limiting the amount of free VEGFA and/or VEGFC and preventing their binding to FLT4. Modulates FLT1 and FLT4 signaling by forming heterodimers.

KDR Antibodies

KDR Antibodies for Homo sapiens (Human)

KDR Antibodies for Danio rerio (Zebrafish) (Brachydanio rerio)

KDR Proteins

KDR Proteins for Mus musculus (Mouse)

KDR Proteins for Homo sapiens (Human)

KDR Proteins for Rattus norvegicus (Rat)

KDR Proteins for Coturnix japonica (Japanese quail) (Coturnix coturnix japonica)

KDR Proteins for Danio rerio (Zebrafish) (Brachydanio rerio)

KDR ELISA Kit

KDR ELISA Kit for Homo sapiens (Human)

KDR ELISA Kit for Mus musculus (Mouse)

KDR ELISA Kit for Rattus norvegicus (Rat)

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