Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase is a protein in humans that is encoded by PKMYT1 gene. Acts as a negative regulator of entry into mitosis (G2 to M transition) by phosphorylation of the CDK1 kinase specifically when CDK1 is complexed to cyclins. Mediates phosphorylation of CDK1 predominantly on 'Thr-14'. Also involved in Golgi fragmentation. May be involved in phosphorylation of CDK1 on 'Tyr-15' to a lesser degree, however tyrosine kinase activity is unclear and may be indirect. May be a downstream target of Notch signaling pathway during eye development.
The following PKMYT1 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
PKMYT1 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA16029A0Rb | PKMYT1 Antibody |
Human | ELISA, IHC |
CSB-PA018073GA01HU | PKMYT1 Antibody |
Human,Mouse,Rat | ELISA,WB |
CSB-PA729561 | Phospho-PKMYT1 (Ser83) Antibody |
Human | ELISA,IHC |
CSB-PA003356 | PKMYT1 Antibody |
Human | WB, IHC, ELISA |
CSB-PA070226 | Phospho-PKMYT1 (S83) Antibody |
Human | IHC, ELISA |
CSB-PA254680 | PKMYT1 Antibody |
Human,Mouse | ELISA,WB |
CSB-PA955430 | PKMYT1 Antibody |
Human,Mouse | ELISA,WB,IHC |
PKMYT1 Proteins for Xenopus laevis (African clawed frog)
Code | Product Name | Source |
---|---|---|
CSB-YP849597XBE CSB-EP849597XBE CSB-BP849597XBE CSB-MP849597XBE CSB-EP849597XBE-B |
Recombinant Xenopus laevis Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase (pkmyt1), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PKMYT1 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP858720HU CSB-EP858720HU CSB-BP858720HU CSB-MP858720HU CSB-EP858720HU-B |
Recombinant Human Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase (PKMYT1) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PKMYT1 Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
---|---|---|
CSB-YP866844MO CSB-EP866844MO CSB-BP866844MO CSB-MP866844MO CSB-EP866844MO-B |
Recombinant Mouse Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase (Pkmyt1) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |