PPIA

PPIA, also known as peptidyl - prolyl cis - trans isomerase A, commonly referred to as cyclophilin A. It functions as an enzyme that catalyzes the isomerization of peptidyl - prolyl bonds, which is crucial in protein folding and maintaining protein structure. It is involved in the T - cell activation pathway and interacts with immunosuppressive drugs like cyclosporin A.
PPIA has been linked to various diseases such as rheumatoid arthritis and viral infections including HIV. Regarding drug development, targeting PPIA is being explored to develop new antiviral and anti - inflammatory agents. Inhibitors of PPIA may offer potential therapeutic strategies for these associated diseases.

Validated Data

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

PPIA Recombinant Monoclonal Antibody (CSB-RA917671A0HU)

Validated Data

Western Blot
Positive WB detected in: Raji whole cell lysate, HepG2 whole cell lysate
All lanes: Cyclophilin A antibody at 1:1500
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 19, 12 kDa
Observed band size: 19 kDa

The following PPIA reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

PPIA Antibodies

PPIA Proteins

PPIA ELISA Kits

PPIA Antibodies

PPIA Antibodies for Homo sapiens (Human)

Code	Product Name	Species Reactivity	Application
CSB-PA018446GA01HU	PPIA Antibody	Human,Mouse,Rat	ELISA,WB
CSB-PA07814D0Rb	PPIA Antibody, Biotin conjugated	Human	ELISA
CSB-PA07814B0Rb	PPIA Antibody, HRP conjugated	Human	ELISA
CSB-PA07814C0Rb	PPIA Antibody, FITC conjugated	Human
CSB-PA07814A0Rb	PPIA Antibody	Human, Mouse	ELISA, WB
CSB-PA005117	PPIA Antibody	Human,Mouse,Rat	WB, ELISA
CSB-PA731155	PPIA Antibody	Human,Mouse,Rat	ELISA,WB
CSB-PA014187	PPIA Antibody	Human,Mouse,Rat	ELISA,WB,IHC
CSB-RA917671A0HU	PPIA Recombinant Monoclonal Antibody	Human	ELISA, WB

PPIA Antibodies for Escherichia coli (strain K12)

Code	Product Name	Species Reactivity	Application
CSB-PA360283XA01ENV	ppiA Antibody	Escherichia coli (strain K12)	ELISA, WB (ensure identification of antigen)

PPIA Antibodies for Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)

Code	Product Name	Species Reactivity	Application
CSB-PA365318XA01FQR	ppiA Antibody	Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)	ELISA, WB (ensure identification of antigen)
CSB-PA365318ZA01EGX	ppiA Antibody	Escherichia coli O6:H1	ELISA, WB (ensure identification of antigen)

PPIA Antibodies for Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)

Code	Product Name	Species Reactivity	Application
CSB-PA322687XA01SXB	ppiA Antibody	Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)	ELISA, WB (ensure identification of antigen)

PPIA Antibodies for Escherichia coli O157:H7

Code	Product Name	Species Reactivity	Application
CSB-PA360284XA01EOD	ppiA Antibody	Escherichia coli O157:H7	ELISA, WB (ensure identification of antigen)
CSB-PA360284ZA01EOD	ppiA Antibody	Escherichia coli O157:H7	ELISA, WB (ensure identification of antigen)

PPIA Proteins

PPIA Proteins for Mus musculus (Mouse)

Code	Product Name	Source
CSB-YP018446MO CSB-EP018446MO CSB-BP018446MO CSB-MP018446MO CSB-EP018446MO-B	Recombinant Mouse Peptidyl-prolyl cis-trans isomerase A (Ppia)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

PPIA Proteins for Streptomyces anulatus (Streptomyces chrysomallus)

Code	Product Name	Source
CSB-YP312330SNK CSB-EP312330SNK CSB-BP312330SNK CSB-MP312330SNK CSB-EP312330SNK-B	Recombinant Streptomyces anulatus Peptidyl-prolyl cis-trans isomerase A (ppiA)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

PPIA Proteins for Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus)

Code	Product Name	Source
CSB-YP318604DXU CSB-EP318604DXU CSB-BP318604DXU CSB-MP318604DXU CSB-EP318604DXU-B	Recombinant Cricetulus griseus Peptidyl-prolyl cis-trans isomerase A (PPIA)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

PPIA Proteins for Rattus norvegicus (Rat)

Code	Product Name	Source
CSB-YP320617RA CSB-EP320617RA CSB-BP320617RA CSB-MP320617RA CSB-EP320617RA-B	Recombinant Rat Peptidyl-prolyl cis-trans isomerase A (Ppia)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

PPIA Proteins for Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)

Code	Product Name	Source
CSB-YP322687SXB CSB-EP322687SXB CSB-BP322687SXB CSB-MP322687SXB CSB-EP322687SXB-B	Recombinant Salmonella typhimurium Peptidyl-prolyl cis-trans isomerase A (ppiA)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

PPIA Proteins for Chlorocebus aethiops (Green monkey) (Cercopithecus aethiops)

Code	Product Name	Source
CSB-YP351207DSU CSB-EP351207DSU CSB-BP351207DSU CSB-MP351207DSU CSB-EP351207DSU-B	Recombinant Chlorocebus aethiops Peptidyl-prolyl cis-trans isomerase A (PPIA)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

PPIA Proteins for Papio anubis (Olive baboon)

Code	Product Name	Source
CSB-YP351208ERI CSB-EP351208ERI CSB-BP351208ERI CSB-MP351208ERI CSB-EP351208ERI-B	Recombinant Papio anubis Peptidyl-prolyl cis-trans isomerase A (PPIA)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

PPIA Proteins for Bos taurus (Bovine)

Code	Product Name	Source
CSB-YP351809BO CSB-EP351809BO CSB-BP351809BO CSB-MP351809BO CSB-EP351809BO-B	Recombinant Bovine Peptidyl-prolyl cis-trans isomerase A (PPIA)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

PPIA Proteins for Homo sapiens (Human)

Code	Product Name	Source
CSB-YP351810HU CSB-EP351810HU CSB-BP351810HU CSB-MP351810HU CSB-EP351810HU-B	Recombinant Human Peptidyl-prolyl cis-trans isomerase A (PPIA)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-EP351810HU1	Recombinant Human Peptidyl-prolyl cis-trans isomerase A (PPIA)	E.coli
CSB-EP351810HU	Recombinant Human Peptidyl-prolyl cis-trans isomerase A (PPIA)	E.coli
CSB-EP351810HU1e1	Recombinant Human Peptidyl-prolyl cis-trans isomerase A (PPIA)	E.coli

PPIA Proteins for Sus scrofa (Pig)

Code	Product Name	Source
CSB-YP352383PI CSB-EP352383PI CSB-BP352383PI CSB-MP352383PI CSB-EP352383PI-B	Recombinant Pig Peptidyl-prolyl cis-trans isomerase A (PPIA)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

PPIA Proteins for Macaca mulatta (Rhesus macaque)

Code	Product Name	Source
CSB-YP352384MOW CSB-EP352384MOW CSB-BP352384MOW CSB-MP352384MOW CSB-EP352384MOW-B	Recombinant Macaca mulatta Peptidyl-prolyl cis-trans isomerase A (PPIA)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

PPIA Proteins for Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)

Code	Product Name	Source
CSB-YP354595MVH CSB-EP354595MVH CSB-BP354595MVH CSB-MP354595MVH CSB-EP354595MVH-B	Recombinant Probable peptidyl-prolyl cis-trans isomerase A (ppiA)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

PPIA Proteins for Escherichia coli (strain K12)

Code	Product Name	Source
CSB-YP360283ENV CSB-EP360283ENV CSB-BP360283ENV CSB-MP360283ENV CSB-EP360283ENV-B	Recombinant Escherichia coli Peptidyl-prolyl cis-trans isomerase A (ppiA)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

PPIA Proteins for Escherichia coli O157:H7

Code	Product Name	Source
CSB-YP360284EOD CSB-BP360284EOD CSB-MP360284EOD CSB-EP360284EOD-B	Recombinant Escherichia coli Peptidyl-prolyl cis-trans isomerase A (ppiA)	Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-EP360284EOD	Recombinant Escherichia coli Peptidyl-prolyl cis-trans isomerase A (ppiA)	E.coli

PPIA Proteins for Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)

Code	Product Name	Source
CSB-YP365318EGX CSB-BP365318EGX CSB-MP365318EGX CSB-EP365318EGX-B	Recombinant Escherichia coli O6:H1 Peptidyl-prolyl cis-trans isomerase A (ppiA)	Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-EP365318EGX	Recombinant Escherichia coli O6:H1 Peptidyl-prolyl cis-trans isomerase A (ppiA)	E.coli

PPIA Proteins for Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori)

Code	Product Name	Source
CSB-YP515898HUV CSB-EP515898HUV CSB-BP515898HUV CSB-MP515898HUV CSB-EP515898HUV-B	Recombinant Helicobacter pylori Peptidyl-prolyl cis-trans isomerase (ppiA)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

PPIA Proteins for Gorilla gorilla gorilla (Western lowland gorilla)

Code	Product Name	Source
CSB-YP604535GGZ CSB-EP604535GGZ CSB-BP604535GGZ CSB-MP604535GGZ CSB-EP604535GGZ-B	Recombinant Gorilla gorilla gorilla Peptidyl-prolyl cis-trans isomerase A (PPIA)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

PPIA Proteins for Symphalangus syndactylus (Siamang) (Hylobates syndactylus)

Code	Product Name	Source
CSB-YP605918HXY CSB-EP605918HXY CSB-BP605918HXY CSB-MP605918HXY CSB-EP605918HXY-B	Recombinant Hylobates syndactylus Peptidyl-prolyl cis-trans isomerase A (PPIA)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

PPIA Proteins for Hylobates lar (Common gibbon) (White-handed gibbon)

Code	Product Name	Source
CSB-YP607325HXW CSB-EP607325HXW CSB-BP607325HXW CSB-MP607325HXW CSB-EP607325HXW-B	Recombinant Hylobates lar Peptidyl-prolyl cis-trans isomerase A (PPIA)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

PPIA Proteins for Saguinus oedipus (Cotton-top tamarin)

Code	Product Name	Source
CSB-YP608712SWB CSB-EP608712SWB CSB-BP608712SWB CSB-MP608712SWB CSB-EP608712SWB-B	Recombinant Saguinus oedipus Peptidyl-prolyl cis-trans isomerase A (PPIA)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

PPIA Proteins for Nomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys)

Code	Product Name	Source
CSB-YP608713NHM CSB-EP608713NHM CSB-BP608713NHM CSB-MP608713NHM CSB-EP608713NHM-B	Recombinant Nomascus leucogenys Peptidyl-prolyl cis-trans isomerase A (PPIA)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

PPIA Proteins for Pan troglodytes (Chimpanzee)

Code	Product Name	Source
CSB-YP608714EQV CSB-EP608714EQV CSB-BP608714EQV CSB-MP608714EQV CSB-EP608714EQV-B	Recombinant Pan troglodytes Peptidyl-prolyl cis-trans isomerase A (PPIA)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

PPIA Proteins for Pan paniscus (Pygmy chimpanzee) (Bonobo)

Code	Product Name	Source
CSB-YP611895EQU CSB-EP611895EQU CSB-BP611895EQU CSB-MP611895EQU CSB-EP611895EQU-B	Recombinant Pan paniscus Peptidyl-prolyl cis-trans isomerase A (PPIA)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

PPIA Proteins for Dictyostelium discoideum (Slime mold)

Code	Product Name	Source
CSB-YP684701DKK CSB-EP684701DKK CSB-BP684701DKK CSB-MP684701DKK CSB-EP684701DKK-B	Recombinant Dictyostelium discoideum Peptidyl-prolyl cis-trans isomerase A (ppiA)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

PPIA Proteins for Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)

Code	Product Name	Source
CSB-YP707530EZX CSB-EP707530EZX CSB-BP707530EZX CSB-MP707530EZX CSB-EP707530EZX-B	Recombinant Pseudomonas aeruginosa Peptidyl-prolyl cis-trans isomerase A (ppiA)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

PPIA Proteins for Pongo pygmaeus (Bornean orangutan)

Code	Product Name	Source
CSB-YP712893EXP CSB-EP712893EXP CSB-BP712893EXP CSB-MP712893EXP CSB-EP712893EXP-B	Recombinant Pongo pygmaeus Peptidyl-prolyl cis-trans isomerase A (PPIA)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

PPIA Proteins for Aotus trivirgatus (Three-striped night monkey) (Douroucouli)

Code	Product Name	Source
CSB-YP728571DNI CSB-EP728571DNI CSB-BP728571DNI CSB-MP728571DNI CSB-EP728571DNI-B	Recombinant Aotus trivirgatus Peptidyl-prolyl cis-trans isomerase A (PPIA)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

PPIA Proteins for Felis catus (Cat) (Felis silvestris catus)

Code	Product Name	Source
CSB-YP815495CA CSB-EP815495CA CSB-BP815495CA CSB-MP815495CA CSB-EP815495CA-B	Recombinant Cat Peptidyl-prolyl cis-trans isomerase A (PPIA)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

PPIA Proteins for Oryctolagus cuniculus (Rabbit)

Code	Product Name	Source
CSB-YP874675RB CSB-EP874675RB CSB-BP874675RB CSB-MP874675RB CSB-EP874675RB-B	Recombinant Rabbit Peptidyl-prolyl cis-trans isomerase A (PPIA)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

PPIA Proteins for Mycobacterium leprae (strain TN)

Code	Product Name	Source
CSB-YP874969MVN CSB-EP874969MVN CSB-BP874969MVN CSB-MP874969MVN CSB-EP874969MVN-B	Recombinant Probable peptidyl-prolyl cis-trans isomerase A (ppiA)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli