Sphingosine 1-phosphate receptor 1 is a protein in humans that is encoded by S1PR1 gene. G-protein coupled receptor for the bioactive lysosphingolipid sphingosine 1-phosphate (S1P) that seems to be coupled to the G(i) subclass of heteromeric G proteins. Signaling leads to the activation of RAC1, SRC, PTK2/FAK1 and MAP kinases. Plays an important role in cell migration, probably via its role in the reorganization of the actin cytoskeleton and the formation of lamellipodia in response to stimuli that increase the activity of the sphingosine kinase SPHK1. Required for normal chemotaxis toward sphingosine 1-phosphate. Required for normal embryonic heart development and normal cardiac morphogenesis. Plays an important role in the regulation of sprouting angiogenesis and vascular maturation. Inhibits sprouting angiogenesis to prevent excessive sprouting during blood vessel development.
The following S1PR1 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
S1PR1 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA020650GA01HU | S1PR1 Antibody |
Human,Mouse,Rat | ELISA,WB |
CSB-PA002247 | S1PR1 Antibody |
Human,Mouse,Rat | WB, IF, ELISA |
CSB-PA007881 | Phospho-S1PR1 (T236) Antibody |
Human,Mouse,Rat | WB, IF, ELISA |
CSB-PA007898 | S1PR1 Antibody |
Human | WB, IHC, IF, ELISA |
CSB-PA020650LA01HU | S1PR1 Antibody |
Human, Mouse | ELISA, WB, IHC, IF |
CSB-PA020650LC01HU | S1PR1 Antibody, FITC conjugated |
Human | |
CSB-PA193689 | S1PR1 Antibody |
Human,Mouse,Rat | ELISA,WB |
CSB-PA241754 | S1PR1 Antibody |
Human,Mouse,Rat | ELISA,WB |
CSB-RA923827A0HU | S1PR1 Recombinant Monoclonal Antibody |
Human | ELISA, WB |
S1PR1 Antibodies for Danio rerio (Zebrafish) (Brachydanio rerio)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA875293XA01DIL | s1pr1 Antibody |
Danio rerio (Zebrafish) (Brachydanio rerio) | ELISA, WB (ensure identification of antigen) |
S1PR1 Proteins for Danio rerio (Zebrafish) (Brachydanio rerio)
Code | Product Name | Source |
---|---|---|
CSB-CF875293DIL | Recombinant Danio rerio Sphingosine 1-phosphate receptor 1 (s1pr1) |
in vitro E.coli expression system |
CSB-YP875293DIL1 CSB-EP875293DIL1 CSB-BP875293DIL1 CSB-MP875293DIL1 CSB-EP875293DIL1-B |
Recombinant Danio rerio Sphingosine 1-phosphate receptor 1 (s1pr1), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
S1PR1 Proteins for Bos taurus (Bovine)
Code | Product Name | Source |
---|---|---|
CSB-CF685723BO | Recombinant Bovine Sphingosine 1-phosphate receptor 1 (S1PR1) |
in vitro E.coli expression system |
CSB-YP685723BO1 CSB-EP685723BO1 CSB-BP685723BO1 CSB-MP685723BO1 CSB-EP685723BO1-B |
Recombinant Bovine Sphingosine 1-phosphate receptor 1 (S1PR1), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
S1PR1 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-CF020650HU | Recombinant Human Sphingosine 1-phosphate receptor 1 (S1PR1) |
in vitro E.coli expression system |
CSB-YP020650HU1 CSB-EP020650HU1 CSB-BP020650HU1 CSB-MP020650HU1 CSB-EP020650HU1-B |
Recombinant Human Sphingosine 1-phosphate receptor 1 (S1PR1), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
S1PR1 Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
---|---|---|
CSB-CF020650MO | Recombinant Mouse Sphingosine 1-phosphate receptor 1 (S1pr1) |
in vitro E.coli expression system |
CSB-YP020650MO1 CSB-EP020650MO1 CSB-BP020650MO1 CSB-MP020650MO1 CSB-EP020650MO1-B |
Recombinant Mouse Sphingosine 1-phosphate receptor 1 (S1pr1), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
S1PR1 Proteins for Rattus norvegicus (Rat)
Code | Product Name | Source |
---|---|---|
CSB-CF020650RA | Recombinant Rat Sphingosine 1-phosphate receptor 1 (S1pr1) |
in vitro E.coli expression system |
CSB-YP020650RA1 CSB-EP020650RA1 CSB-BP020650RA1 CSB-MP020650RA1 CSB-EP020650RA1-B |
Recombinant Rat Sphingosine 1-phosphate receptor 1 (S1pr1), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |