TNFAIP6 (Tumor Necrosis Factor Alpha-Induced Protein 6), commonly known as TSG-6 (TNF-stimulated gene 6), is a secreted glycoprotein of the hyaluronan-binding protein family. Induced by pro-inflammatory cytokines like TNF-α and IL-1β, it forms complexes with hyaluronan (HA) and inter-alpha-inhibitor (IαI) to regulate HA matrix organization and suppress inflammatory cell infiltration.
Dysregulated TNFAIP6 is linked to autoimmune diseases (e.g., rheumatoid arthritis, with elevated levels in synovial fluid), inflammatory disorders, and cancers (e.g., breast cancer metastasis). Recombinant TSG-6 shows preclinical promise for inflammation and tissue repair, while targeted inhibition is under early-stage investigation for cancer therapy.
Recombinant Human Tumor necrosis factor-inducible gene 6 protein (TNFAIP6) (CSB-EP023959HU)
Validated Data
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
TNFAIP6 Antibody (CSB-PA023959LA01HU)
Validated Data
Immunohistochemistry of paraffin-embedded human ovarian cancer using CSB-PA023959LA01HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human skeletal muscle tissue using CSB-PA023959LA01HU at dilution of 1:100
Human Tumor necrosis factor-inducible gene 6 protein(TNFAIP6) ELISA kit (CSB-EL023959HU)
Validated Data
Code: CSB-EL023959HU
Size: 96T,5×96T,10×96T
Sensitivity: 11.75 ng/ml
Detection Range: 47 ng/ml - 3000 ng/ml
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
The following TNFAIP6 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
TNFAIP6 Antibodies for Homo sapiens (Human)
| Code | Product Name | Species Reactivity | Application |
|---|---|---|---|
| CSB-PA023959LD01HU | TNFAIP6 Antibody, Biotin conjugated | Human | ELISA |
| CSB-PA023959LC01HU | TNFAIP6 Antibody, FITC conjugated | Human | |
| CSB-PA023959LA01HU | TNFAIP6 Antibody | Human | ELISA, IHC |
| CSB-PA023959GA01HU | TNFAIP6 Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA050273 | TNFAIP6 Antibody | Human,Mouse | WB, IHC, IF, ELISA |
TNFAIP6 Proteins for Homo sapiens (Human)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP023959HU CSB-MP023959HU CSB-EP023959HU-B |
Recombinant Human Tumor necrosis factor-inducible gene 6 protein (TNFAIP6) | Yeast Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP023959HU | Recombinant Human Tumor necrosis factor-inducible gene 6 protein (TNFAIP6) | E.coli |
| CSB-BP023959HU | Recombinant Human Tumor necrosis factor-inducible gene 6 protein (TNFAIP6) | Baculovirus |
TNFAIP6 ELISA Kit for Homo sapiens (Human)
| Code | Product Name | Sample Types | Sensitivity |
|---|---|---|---|
| CSB-EL023959HU | Human Tumor necrosis factor-inducible gene 6 protein(TNFAIP6) ELISA kit | serum, plasma, tissue homogenates | 11.75 ng/ml |