TNFSF8 is a gene providing an instruction of making a protein named tumor necrosis factor ligand superfamily member 8 (usually abbreviated as TNFSF8). The protein encoded by this gene is also called CD30L, which is a specific ligand for CD30. The cDNA of CD30L was cloned in 1993 and it was determined that it belongs to the TNF superfamily. CD30L is a type II membrane glycoprotein with a molecular weight of 40kDa. CD30L is mainly expressed on activated CD4+ T cells, activated CD8+ T cells, macrophages and dendritic cells. The expression of CD30L on CD4+ and CD8+ T cells can stimulate proliferation and increased secretion of cytokines, such as IL2, IL4, IFN-γ and TNF-α.
Validated Data
Greater than 94% as determined by SDS-PAGE.
Immobilized CD30 (CSB-MP023983HU1) at 5 μg/ml can bind human CD30L, the EC50 is 4.169-6.360 ng/ml.
The following TNFSF8 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
TNFSF8 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA951710 | TNFSF8 Antibody |
Human,Mouse | ELISA,WB |
CSB-PA006282 | TNFSF8 Antibody |
Human | WB, ELISA |
CSB-PA009041 | TNFSF8 Antibody |
Human,Mouse | WB, IF, ELISA |
TNFSF8 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-CF023996HU | Recombinant Human Tumor necrosis factor ligand superfamily member 8 (TNFSF8) |
in vitro E.coli expression system |
CSB-YP023996HU1 CSB-EP023996HU1 CSB-BP023996HU1 CSB-MP023996HU1 CSB-EP023996HU1-B |
Recombinant Human Tumor necrosis factor ligand superfamily member 8 (TNFSF8), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-MP023996HU1 | Recombinant Human Tumor necrosis factor ligand superfamily member 8 (TNFSF8), partial (Active) |
Mammalian cell |
CSB-MP023996HU1c9 | Recombinant Human Tumor necrosis factor ligand superfamily member 8 (TNFSF8), partial (Active) |
Mammalian cell |
TNFSF8 Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
---|---|---|
CSB-CF023996MO | Recombinant Mouse Tumor necrosis factor ligand superfamily member 8 (Tnfsf8) |
in vitro E.coli expression system |
CSB-YP023996MO1 CSB-EP023996MO1 CSB-BP023996MO1 CSB-MP023996MO1 CSB-EP023996MO1-B |
Recombinant Mouse Tumor necrosis factor ligand superfamily member 8 (Tnfsf8), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
TNFSF8 ELISA Kit for Mus musculus (Mouse)
Code | Product Name | Sample Types | Sensitivity |
---|---|---|---|
CSB-E04715m | Mouse Soluble Cluster of differentiation 30 ligand,sCD30L ELISA Kit |
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