TRIM72, also known as Mitofusin 53, is a multifunctional protein with a key role in membrane repair and cellular stress responses. It possesses a RING-finger domain, which is critical for its E3 ubiquitin ligase activity. TRIM72 functions in the repair of damaged cell membranes, particularly in skeletal muscle and myocardium, by recruiting vesicles to the injury site and facilitating membrane fusion. This protein is involved in various signaling pathways, including PI3K/Akt and NF-κB, and is associated with diseases such as Duchenne muscular dystrophy and myocardial infarction. Research on TRIM72 has led to potential therapeutic applications, including gene therapy for muscular dystrophies and its exploration as a target for cancer treatment.
Recombinant Human Tripartite motif-containing protein 72 (TRIM72), partial (CSB-EP744394HU)
Validated Data
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
TRIM72 Antibody (CSB-PA080146)
Validated Data
Immunohistochemical analysis of paraffin-embedded Mouse PancreasTissue using TRIM72 Polyclonal Antibody.
Western blot analysis of Mouse skeletal muscle using TRIM72 Polyclonal Antibody.
Human Tripartite motif-containing protein 72(TRIM72) ELISA kit (CSB-EL024511HU)
Validated Data
Code: CSB-EL024511HU
Size: 96T,5×96T,10×96T
Sensitivity: 6.25 pg/mL
Detection Range: 25 pg/mL-1600 pg/mL
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
The following TRIM72 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
TRIM72 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA080146 | TRIM72 Antibody | Human,Mouse,Rat | WB, IHC |
CSB-PA744394ZA01HU | TRIM72 Antibody | Homo sapiens | ELISA, WB (ensure identification of antigen) |
TRIM72 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP744394HU CSB-EP744394HU-B |
Recombinant Human Tripartite motif-containing protein 72 (TRIM72), partial | Yeast In Vivo Biotinylation in E.coli |
CSB-MP744394HU | Recombinant Human Tripartite motif-containing protein 72 (TRIM72), partial | Mammalian cell |
CSB-EP744394HU1(M) | Recombinant Human Tripartite motif-containing protein 72 (TRIM72), partial | E.coli |
CSB-EP744394HU1 | Recombinant Human Tripartite motif-containing protein 72 (TRIM72), partial | E.coli |
CSB-BP744394HU | Recombinant Human Tripartite motif-containing protein 72 (TRIM72), partial | Baculovirus |
CSB-EP744394HU | Recombinant Human Tripartite motif-containing protein 72 (TRIM72), partial | E.coli |
TRIM72 ELISA Kit for Homo sapiens (Human)
Code | Product Name | Sample Types | Sensitivity |
---|---|---|---|
CSB-EL024511HU | Human Tripartite motif-containing protein 72(TRIM72) ELISA kit | serum, plasma, tissue homogenates, cell lysates | 6.25 pg/mL |