usp Antibody

1. Context-dependent functional properties of EcR and USP receptors in Drosophila cell survival. PMID: 26250909
2. nutrition controls ecdysone biosynthesis partially via FoxO-Usp prior to critical weight, ensuring that growth only stops once larvae have achieved a target nutritional status. PMID: 25421296
3. The results suggest that normal larval to pupal maturation in this mecopteran model insect requires the involvement of a distinct endocrine axis of USP binding to its own endogenous terpenoid ligand. PMID: 23211750
4. PKC mediates USP phosphorylation at Ser35 in Kc and S2 cells, which regulates 20-hydroxyecdysone signaling. PMID: 23136906
5. sumoylation of Usp protein can be an important factor in modulating its activity by changing molecular interactions PMID: 22676916
6. Ecdysone and NO mediate gene regulation by competing EcR/Usp and E75A nuclear receptors during Drosophila development PMID: 21981918
7. Ecdysone receptor and USP were expressed in numerous adult tissues, but receptor activity varied depending on tissue type and adult age. Receptor activity is reduced when a constitutively inactive ecdysone receptor is present. PMID: 21507325
8. Data show that ultraspiracle- and ecdysteroid receptor-mediated transcriptional activity not only depends on an interaction between the ecdysteroid receptor and a given hormone response element, but is also modified by surrounding DNA sequences. PMID: 21316451
9. stability of the ecdysone receptor (EcR) is regulated in a cooperative manner by the AB-domains of EcR and Ultraspiracle PMID: 19711356
10. The heterodimerization partner Usp increased DNA binding of ecdysone receptor considerably PMID: 19750549
11. USP both represses and activates a gene affecting furrow movement, the ecdysone-responsive Z1 isoform of Broad-Complex, and we report additional usp mutant phenotypes PMID: 11804781
12. ecdysteroids are capable of inducing heterodimer formation between EcR and USP PMID: 12084064
13. USP activates transcription and binds ligand with a functional outcome of enhanced promoter activity PMID: 12473098
14. truncation of its N-terminal A/B region changes molecular characteristics of ultraspiracle, considerably weakening its oligomerization potential under the same experimental conditions PMID: 12674500
15. findings show that the EcR-USP ecdysone receptor is first activated in the extraembryonic amnioserosa, implicating this tissue as a source of active ecdysteroids in the early embryo PMID: 12958367
16. Analysis of the role of ligand-binding domains in the heterodimerization of ecdysone receptor and ultraspiracle protein. PMID: 14594447
17. results indicate that EcR and Usp can enter the nucleus independently, but cotransport of both receptors mediated by dimerization via the ligand binding domains is possible even in the absence of hormone PMID: 17570142
18. data confirm that EcR and Usp can enter the nucleus independently and that intracellular localization is regulated individually for each receptor PMID: 17570491
19. A bimolecular fluorescence complementation (BiFC) method was used to directly analyze the formation of the EcR/Usp complex. PMID: 18771703
20. heterodimeric complex EcR-B1/Usp mediates the ecdysone-dependent VM32E transcriptional activation in the main body follicle cells. PMID: 19389369

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KEGG: dme:Dmel_CG4380

STRING: 7227.FBpp0305937

UniGene: Dm.25