ANGPTL4, known as angiopoietin-like 4 protein, also has aliases like HFARP and FIAF. It is a secreted glycoprotein. ANGPTL4 inhibits lipoprotein lipase activity, regulating lipid metabolism. It is involved in the PPAR signaling pathway, which is crucial for lipid and glucose homeostasis.
ANGPTL4 is associated with various diseases, including obesity, diabetes, and cardiovascular diseases. In drug development, ANGPTL4 is emerging as a potential therapeutic target. Researchers are exploring monoclonal antibodies and small - molecule inhibitors against ANGPTL4 to improve lipid profiles and treat related metabolic disorders.
Recombinant Human Angiopoietin-related protein 4 (ANGPTL4), partial (CSB-EP866314HU1)
Validated Data
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-RP101444h could indicate that this peptide derived from E.coli-expressed Homo sapiens (Human) ANGPTL4.
Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-RP101444h could indicate that this peptide derived from E.coli-expressed Homo sapiens (Human) ANGPTL4.
ANGPTL4 Antibody (CSB-PA866314ESR2HU)
Validated Data
Western blot
All lanes: Angiopoietin-related protein 4 antibody at 2μg/ml + Mouse heart tissue
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 46, 41, 27 kDa
Observed band size: 46 kDa
Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA866314ESR2HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human skeletal muscle tissue using CSB-PA866314ESR2HU at dilution of 1:100
The following ANGPTL4 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
ANGPTL4 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA001712GA01HU | ANGPTL4 Antibody | Human | ELISA,IHC |
CSB-PA866314ESR1HU | ANGPTL4 Antibody | Human | ELISA, IHC |
CSB-PA866314ESR2HU | ANGPTL4 Antibody | Human, Mouse | ELISA, WB, IHC |
CSB-PA005044 | ANGPTL4 Antibody | Human,Mouse,Rat | WB, ELISA |
CSB-PA261295 | ANGPTL4 Antibody | Human | ELISA,IHC |
CSB-PA231310 | ANGPTL4 Antibody | Human | ELISA,IHC |
CSB-PA866314EA01HU | ANGPTL4 Antibody | Human | ELISA, WB |
CSB-PA866314EB01HU | ANGPTL4 Antibody, HRP conjugated | Human | ELISA |
CSB-PA866314EC01HU | ANGPTL4 Antibody,FITC conjugated | Human |
ANGPTL4 Proteins for Bos taurus (Bovine)
Code | Product Name | Source |
---|---|---|
CSB-YP645629BO CSB-EP645629BO CSB-BP645629BO CSB-MP645629BO CSB-EP645629BO-B |
Recombinant Bovine Angiopoietin-related protein 4 (ANGPTL4) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ANGPTL4 Proteins for Sus scrofa (Pig)
Code | Product Name | Source |
---|---|---|
CSB-YP652704PI CSB-EP652704PI CSB-BP652704PI CSB-MP652704PI CSB-EP652704PI-B |
Recombinant Pig Angiopoietin-related protein 4 (ANGPTL4) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ANGPTL4 Proteins for Rattus norvegicus (Rat)
Code | Product Name | Source |
---|---|---|
CSB-YP761460RA CSB-EP761460RA CSB-BP761460RA CSB-MP761460RA CSB-EP761460RA-B |
Recombinant Rat Angiopoietin-related protein 4 (Angptl4) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ANGPTL4 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP866314HU CSB-EP866314HU CSB-BP866314HU CSB-MP866314HU CSB-EP866314HU-B |
Recombinant Human Angiopoietin-related protein 4 (ANGPTL4) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-EP866314HU1 | Recombinant Human Angiopoietin-related protein 4 (ANGPTL4), partial | E.coli |
ANGPTL4 ELISA Kit for Homo sapiens (Human)
Code | Product Name | Sample Types | Sensitivity |
---|---|---|---|
CSB-EL001712HU | Human Angiopoietin-related protein 4(ANGPTL4) ELISA kit | serum, plasma, tissue homogenates | 0.39 ng/mL |
ANGPTL4 ELISA Kit for Mus musculus (Mouse)
Code | Product Name | Sample Types | Sensitivity |
---|---|---|---|
CSB-EL001712MO | Mouse Angiopoietin-related protein 4(ANGPTL4) ELISA kit | serum, plasma, tissue homogenates | 0.78 pg/mL |
ANGPTL4 ELISA Kit for Rattus norvegicus (Rat)
Code | Product Name | Sample Types | Sensitivity |
---|---|---|---|
CSB-EL001712RA | Rat Angiopoietin-related protein 4(ANGPTL4) ELISA kit | serum, plasma, cell culture supernates, tissue homogenates, bronchoalveolar lavage fluid, urine | 1.95 pg/mL |